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Anti-DCT Polyclonal Antibody (Synonyms: TYRP2, Tyrosinase-related protein 2 (TRP-2;TRP2), L-dopachrome tautome...)
Catalog No. TMAB-00536 Copy Product Info
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Anti-DCT Polyclonal Antibody is a Rabbit antibody targeting DCT. Anti-DCT Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-DCT Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00536
Synonyms TYRP2, Tyrosinase-related protein 2 (TRP-2;TRP2), L-dopachrome tautomerase, L-dopachrome Delta-isomerase, DT, DCT
Anti-DCT Polyclonal Antibody is a Rabbit antibody targeting DCT. Anti-DCT Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-DCT Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-DCT Polyclonal Antibody is a Rabbit antibody targeting DCT. Anti-DCT Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | TYRP2, Tyrosinase-related protein 2 (TRP-2;TRP2), L-dopachrome tautomerase, L-dopachrome Delta-isomerase, DT, DCT |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Rabbit,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Human melanoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TRP2) Polyclonal Antibody, Unconjugated (TMAB-00536) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Melanosome membrane; Single-pass type I membrane protein. Melanocytes and retinal pigmented epithelium. |
| Tissue Specificity | Melanocytes and retinal pigmented epithelium. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | DCT (Dopachrome Tautomerase) is a Protein Coding gene. Diseases associated with DCT include Microphthalmia and Hermansky-Pudlak Syndrome 3. Among its related pathways are Metabolism and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and dopachrome isomerase activity. An important paralog of this gene is TYRP1. |
| Immunogen | KLH conjugated synthetic peptide: human TRP2 |
| Antigen Species | Human |
| Gene Name | DCT |
| Gene ID | |
| Protein Name | L-dopachrome tautomerase |
| Uniprot ID | |
| Biology Area | Cell differentiation,Oxidative Stress,Ectoderm,Oxidative stress |
| Function | Involved in regulating eumelanin and phaeomelanin levels. |
| Molecular Weight | Theoretical: 61 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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