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Anti-Phospho-NEDD4L (Ser448) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NEDD4L (Ser448). Anti-Phospho-NEDD4L (Ser448) Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $216 | 7-10 days | |
100 μL | $316 | 7-10 days |
Description | Anti-Phospho-NEDD4L (Ser448) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NEDD4L (Ser448). Anti-Phospho-NEDD4L (Ser448) Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
Reactivity | Human |
Application | |
Recommended Dose | WB: 1:1000-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human NEDD4L around the phosphorylation site of Ser448 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 110-120 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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