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TargetMol | Compound Library

Anti-Metabolism Disease Compound Library

Catalog No. L5200

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1544 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5200

Anti-Metabolism Disease Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1544 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or NMPA;
  • Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
Endogenous Metabolite
Cytochromes P450
Antibacterial
Dehydrogenase
AMPK
PDE
PPAR
PI3K
NF-κB
ROS
COX
Antibiotic
mTOR
Parasite
Glucocorticoid Receptor
Reactive Oxygen Species
Potassium Channel
HSP
MAO
HIV Protease
Ferroptosis
Antifungal
Akt
DNA/RNA Synthesis
Calcium Channel
Carbonic Anhydrase
FAAH
Interleukin
Phosphatase
GSK-3
Monoamine Oxidase
Lipoxygenase
Mitophagy
Influenza Virus
Mitochondrial Metabolism
RAAS
SARS-CoV
Retinoid Receptor
HIF/HIF Prolyl-Hydroxylase
FXR
Casein Kinase
Adrenergic Receptor
Caspase
TNF
DPP-4
Glucosidase
Phospholipase
Wnt/beta-catenin
ERK
Nrf2
Virus Protease
Glucagon Receptor
CDK
Transferase
ROCK
IDO
5-HT Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Reductase
NADPH
MMP
JNK
AChR
GPCR
Sodium Channel
Angiotensin-converting Enzyme (ACE)
glycosidase
HMG-CoA Reductase
GABA Receptor
Lipase
IL Receptor
DNA-PK
Histamine Receptor
Beta Amyloid
STAT
p38 MAPK
PKA
ATM/ATR
HCV Protease
Prostaglandin Receptor
NO Synthase
HBV
AhR
Adenosine Receptor
PARP
Bcl-2 Family
Glucokinase
Cannabinoid Receptor
PKC
SGLT
transporter
S6 Kinase
Fatty Acid Synthase
HIF
ROR
Serine Protease
VEGFR
DHFR
Estrogen Receptor/ERR
Glutathione Peroxidase
Aryl Hydrocarbon Receptor
Tyrosinase
HSV
IκB/IKK
Opioid Receptor
ATPase
Cholinesterase (ChE)
Hydroxylase
TRP/TRPV Channel
Stearoyl-CoA Desaturase (SCD)
PDK
Anti-infection
Estrogen/progestogen Receptor
Liver X Receptor
Isocitrate Dehydrogenase (IDH)
Xanthine Oxidase
P-gp
IGF-1R
Dopamine Receptor
Antifolate
Factor Xa
NAMPT
Reverse Transcriptase
Ras
Proteasome
Topoisomerase
PKM
Sirtuin
HDAC
Thrombin
UGT
PAI-1
Trk receptor
TGF-beta/Smad
Acyltransferase
Neprilysin
Cysteine Protease
MAGL
TLR
Src
iGluR
Lipid
FLT
MDM-2/p53
GPCR19
JAK
Chloride channel
p53
ATP Citrate Lyase
Phosphorylase
MEK
SGK
Drug Metabolite
Aminopeptidase
Microtubule Associated
c-Met/HGFR
EGFR
OAT
RSV
NOS
LDL
PGC-1α
Norepinephrine
Antioxidant
PDGFR
GluR
DNA
CETP
CaMK
NOD-like Receptor (NLR)
Aurora Kinase
FGFR
ALK
ADC Cytotoxin
P2Y Receptor
Immunology/Inflammation related
Hexokinase
MAPK
Thyroid hormone receptor(THR)
Integrin
Serotonin Transporter
SIK
Endothelin Receptor
Epigenetic Reader Domain
Decarboxylase
c-RET
TAM Receptor
Serine/threonin kinase
Leukotriene Receptor
OXPHOS
Acetyl-CoA Carboxylase
FKBP
NADPH-oxidase
Tyrosine Kinases
E1/E2/E3 Enzyme
Adiponectin Receptor
ABC Transporter
CCR
ribosome
Annexin A
Histone Methyltransferase
MRP
Antifection
Androgen Receptor
Vasopressin Receptor
Carboxypeptidase
ROS Kinase
Amino Acids and Derivatives
Cell Cycle Arrest
Chk
PLK
Complement System
Syk
NPC1L1
Tie-2
Hedgehog/Smoothened
Adenosine Deaminase
Proton pump
Monocarboxylate transporter
MTP
Amylase
CXCR
Epoxide Hydrolase
Pyroptosis
MLK
PERK
ATG
Nucleoside Antimetabolite/Analog
Sigma receptor
CFTR
BACE
RANKL/RANK
GRK
Antiviral
c-Kit
Glutaminase
Adenylate cyclase
Bcr-Abl
OX Receptor
Survivin
ASK
Cuproptosis
Progesterone Receptor
Rho
PAK
Gap Junction Protein
NOD
Galectin
PAFR
Gamma-secretase
NMDAR
PANoptosis
c-Fms
Protease
PI4K
S1P Receptor
Aconitase
Cholecystokinin Receptor
LDLR
CSF-1R
Myosin
FLAP
Smo
DNA Alkylation
Thioredoxin
Beta-Secretase
Glutathione reductase
FOXO
Neurokinin receptor
RAR/RXR
DprE1
DNA Alkylator/Crosslinker
Melatonin Receptor
Prolyl Endopeptidase (PREP)
FABP
DNA gyrase
Guanylate cyclase
Bradykinin Receptor
PTEN
Cadherin
Huntingtin
LRRK2
Free radical scavengers
GluCls
Hydrogenase
stilbene oxidase
LTR
Histone Demethylase
N-Acetylglucosaminyltransferase
NR4A
IAP
Monoamine Transporter
Anion Exchanger
PROTAC Linker
p62
CRISPR/Cas9
Imidazoline Receptor
Advanced Glycation End Products
YAP
IFNAR
Necroptosis
Bcl-6
Pim
MT Receptor
Na-K-Cl cotransporter
Molecular Glues
Bombesin Receptor
Telomerase
hCE
TMV
LPA Receptor
DNA Methyltransferase
BMI-1
Transaminase
LPL Receptor
RIP kinase
BCRP
PGE Synthase
Urea Transporter
FAK
Kinesin
Mdm2
CAT
GSNOR
Arginase
DYRK
c-Myc
CaSR
AIM2
Histone Acetyltransferase
MELK
GST
Aromatase
Dipeptidyl Peptidase
REV-ERB
Platelet aggregation
IRAK
PD-1/PD-L1

Keywords