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Anti-Metabolism Disease Compound Library

Catalog No. L5200
  Library Compound List   Excel SDF

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1544 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 1544 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or NMPA;
  • Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L5200)

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..
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Library Composition

Autophagy (239)
Apoptosis (188)
P450 (155)
Endogenous Metabolite (125)
Dehydrogenase (85)
AMPK (81)
Antibacterial (80)
PDE (77)
PPAR (71)
PI3K (55)
Antibiotic (51)
COX (49)
Glucocorticoid Receptor (39)
MAO (37)
Reactive Oxygen Species (35)
HSP (34)
HIV Protease (34)
mTOR (32)
Parasite (31)
Potassium Channel (30)
Ferroptosis (30)
FAAH (28)
Carbonic Anhydrase (27)
NF-κB (27)
Akt (26)
Lipoxygenase (25)
Calcium Channel (24)
Mitophagy (24)
Proteasome (24)
GSK-3 (24)
Antifungal (24)
Phosphatase (24)
Phospholipase (23)
Influenza Virus (22)
DNA/RNA Synthesis (22)
Retinoid Receptor (22)
RAAS (22)
Casein Kinase (21)
HIF/HIF Prolyl-Hydroxylase (20)
Mitochondrial Metabolism (20)
Monoamine Oxidase (20)
FXR (19)
DPP-4 (18)
ROCK (17)
Glucosidase (17)
NADPH (17)
5-HT Receptor (16)
CDK (16)
Transferase (16)
AChR (15)
HMG-CoA Reductase (15)
Adrenergic Receptor (15)
SARS-CoV (14)
GPR (14)
Indoleamine 2,3-Dioxygenase (IDO) (13)
Reductase (13)
HCV Protease (12)
Virus Protease (12)
PKA (12)
Prostaglandin Receptor (12)
AhR (12)
Sodium Channel (12)
Adenosine Receptor (12)
IL Receptor (12)
ATM/ATR (12)
HIF (11)
Glucokinase (11)
MMP (11)
SGLT (11)
TNF (11)
PARP (11)
Fatty Acid Synthase (11)
GABA Receptor (11)
ERK (11)
HBV (11)
DHFR (11)
DNA-PK (11)
S6 Kinase (11)
Lipase (11)
Histamine Receptor (11)
transporter (10)
Wnt/beta-catenin (10)
ROR (10)
Tyrosinase (10)
PKC (10)
Caspase (9)
ROS (9)
Hydroxylase (9)
Estrogen/progestogen Receptor (9)
Liver X Receptor (9)
Cannabinoid Receptor (9)
Serine Protease (9)
Estrogen Receptor/ERR (9)
NO Synthase (8)
HSV (8)
IκB/IKK (8)
Thrombin (8)
Reverse Transcriptase (8)
Isocitrate Dehydrogenase (IDH) (8)
STAT (8)
Antifolate (8)
PDK (8)
ATPase (8)
Interleukin (8)
Xanthine Oxidase (8)
NAMPT (8)
Glutathione Peroxidase (8)
JNK (8)
Factor Xa (8)
Aryl Hydrocarbon Receptor (8)
AChE (8)
Nrf2 (7)
UGT (7)
HDAC (7)
IDO (7)
Cysteine Protease (7)
Lipid (7)
PAI-1 (7)
Dopamine Receptor (7)
PKM (7)
Glucagon Receptor (7)
Stearoyl-CoA Desaturase (SCD) (7)
Topoisomerase (7)
Opioid Receptor (6)
Phosphorylase (6)
Acyltransferase (6)
Sirtuin (6)
VEGFR (6)
TRP/TRPV Channel (6)
Src (6)
Neprilysin (6)
Aminopeptidase (6)
P-gp (6)
p38 MAPK (5)
BCL (5)
Beta Amyloid (5)
SGK (5)
CETP (5)
FLT (5)
Chloride channel (5)
iGluR (5)
MEK (5)
Androgen Receptor (5)
c-Met/HGFR (5)
Microtubule Associated (5)
ribosome (4)
Aurora Kinase (4)
RSV (4)
GluR (4)
CCR (4)
CAT (4)
GPCR19 (4)
NOS (4)
Anti-infection (4)
ATP Citrate Lyase (4)
Serine/threonin kinase (4)
JAK (4)
Norepinephrine (4)
TGF-beta/Smad (4)
DNA (4)
LDL (4)
NPC1L1 (3)
Decarboxylase (3)
OAT (3)
IGF-1R (3)
CaMK (3)
Carboxypeptidase (3)
Thyroid hormone receptor(THR) (3)
Antifection (3)
Leukotriene Receptor (3)
c-RET (3)
PERK (3)
SIK (3)
Annexin A (3)
NADPH-oxidase (3)
Adiponectin receptor (3)
BACE (3)
Ras (3)
P2Y Receptor (3)
TAM Receptor (3)
Drug Metabolite (3)
Hexokinase (3)
Vasopressin Receptor (3)
FGFR (3)
Endothelin Receptor (3)
MRP (3)
Integrin (3)
Acetyl-CoA Carboxylase (3)
ABC (3)
ASK (2)
Adenosine deaminase (2)
Neurokinin receptor (2)
Syk (2)
Trk receptor (2)
c-Kit (2)
p53 (2)
GST (2)
MLK (2)
Gap Junction Protein (2)
ROS Kinase (2)
CFTR (2)
Sigma receptor (2)
ALK (2)
PDGFR (2)
Antiviral (2)
Rho (2)
Hedgehog/Smoothened (2)
PAK (2)
MAPK (2)
Glutaminase (2)
Nucleoside Antimetabolite/Analog (2)
cell cycle arrest (2)
Tyrosine Kinases (2)
Chk (2)
Progesterone Receptor (2)
Histone Demethylase (2)
Antioxidant (2)
Amino Acids and Derivatives (2)
Histone Methyltransferase (2)
Proton pump (2)
PGC-1α (2)
E1/E2/E3 Enzyme (2)
EGFR (2)
OX Receptor (2)
Epigenetic Reader Domain (2)
Epoxide Hydrolase (2)
RAR/RXR  (1)
DNA Methyltransferase (1)
BMI-1 (1)
IFNAR (1)
aconitase (1)
DYRK (1)
Platelet aggregation (1)
Free radical scavengers (1)
Tie-2 (1)
DNA Alkylator/Crosslinker (1)
Beta-Secretase (1)
Melatonin Receptor (1)
Galectin (1)
CaSR (1)
LTR (1)
LPL Receptor (1)
Complement System (1)
Monocarboxylate transporter (1)
advanced glycation end products (1)
Mdm2 (1)
Glutathione reductase (1)
Adenylyl cyclase (1)
GSNOR (1)
Transaminase (1)
stilbene oxidase (1)
PGE Synthase (1)
Hydrogenase (1)
TLR (1)
DprE1 (1)
LRRK2 (1)
Arginase (1)
YAP (1)
cholecystokinin (1)
N-Acetylglucosaminyltransferase (1)
Pyroptosis (1)
BCRP (1)
MAGL (1)
c-Fms (1)
Monoamine Transporter (1)
Anion Exchanger (1)
Guanylate cyclase (1)
Smo (1)
PROTAC Linker (1)
Bombesin Receptor (1)
NMDAR (1)
DNA Alkylation (1)
GluCls (1)
Thioredoxin (1)
hCE (1)
Bradykinin Receptor (1)
MELK (1)
DNA gyrase (1)
LPA Receptor (1)
Pim (1)
FLAP (1)
CXCR (1)
Serotonin Transporter (1)
Telomerase (1)
Immunology/Inflammation related (1)
CSF-1R (1)
IAP (1)
PAD (1)
Aromatase (1)
RIP kinase (1)
Bcr-Abl (1)
FABP (1)
GRK (1)
MT Receptor (1)
CRISPR/Cas9 (1)
PI4K (1)
S1P Receptor (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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