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Synonyms: Tumor Necrosis Factor Receptor Superfamily member 5, TNFRSF5, CDw40, CD40L Receptor, CD40, Bp50, B-Cell Surface Antigen CD40

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $72 | 35 days | 35 days | |
| 10 µg | $116 | 35 days | 35 days | |
| 20 µg | $176 | 35 days | 35 days | |
| 50 µg | $310 | 35 days | 35 days | |
| 100 µg | $532 | 35 days | 35 days | |
| 200 µg | $919 | 35 days | 35 days | |
| 500 µg | $1,900 | 35 days | 35 days | |
| 1 mg | $2,730 | 35 days | 35 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | G7PG38 |
| Amino Acid | Glu21-Arg193 |
| Construction | Glu21-Arg193 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Tumor Necrosis Factor Receptor Superfamily member 5, TNFRSF5, CDw40, CD40L Receptor, CD40, Bp50, B-Cell Surface Antigen CD40 |
| Research Background | CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. |
| Molecular Weight | 28-30 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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