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18:1 PEG3000 PE

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Catalog No. TCL-00489
Alias DOPE-PEG3000, 18:1 PEG3000 PE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium

18:1 PEG3000 PE is a PEG lipid functional terminal group utilized in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Liposome nanoparticles (LNPs), modified with biotin and carboxy terminals, can couple with other biomolecules. Such functionalized nanoparticles are employed for targeted labeling of specific cell proteins. Using streptavidin as a linker, the biotinylated PEG lipid-conjugated polymer nanoparticles can bind with biotinylated antibodies on cell surface receptors, providing utility in fluorescence-based imaging and sensing.

18:1 PEG3000 PE

18:1 PEG3000 PE

😃Good
Catalog No. TCL-00489Alias DOPE-PEG3000, 18:1 PEG3000 PE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
18:1 PEG3000 PE is a PEG lipid functional terminal group utilized in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Liposome nanoparticles (LNPs), modified with biotin and carboxy terminals, can couple with other biomolecules. Such functionalized nanoparticles are employed for targeted labeling of specific cell proteins. Using streptavidin as a linker, the biotinylated PEG lipid-conjugated polymer nanoparticles can bind with biotinylated antibodies on cell surface receptors, providing utility in fluorescence-based imaging and sensing.
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Product Introduction

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Description
18:1 PEG3000 PE is a PEG lipid functional terminal group utilized in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Liposome nanoparticles (LNPs), modified with biotin and carboxy terminals, can couple with other biomolecules. Such functionalized nanoparticles are employed for targeted labeling of specific cell proteins. Using streptavidin as a linker, the biotinylated PEG lipid-conjugated polymer nanoparticles can bind with biotinylated antibodies on cell surface receptors, providing utility in fluorescence-based imaging and sensing.
SynonymsDOPE-PEG3000, 18:1 PEG3000 PE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
Chemical Properties
Molecular Weight3000(Average)
Formula(C2H4O)nC43H80NO10P.NH3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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