Skin Disease Modeling

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Disease Modeling

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Skin Disease Modeling

Dermatological Disease Modeling Products are widely used in establishing models of psoriasis, atopic dermatitis, skin cancer, and other skin-related disorders. TargetMol offers inducers such as IMQ (Imiquimod), IL-17/IL-23, Capsaicin, and Terephthalic acid, which are suitable for modeling chronic inflammatory skin diseases and skin tumors. These products support the exploration of disease mechanisms and the development of topical therapeutics for dermatological conditions.

IL-23 Protein, Mouse, Recombinant (His)

TMPY-03526

Expression system: HEK293 Cells
Length: 1-196 & 1-335, Full Length
Activity: ELISA、Cells

$245

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Cited

Capsaicin

T1062404-86-4

Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.

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Calcipotriol

T14856112965-21-6

Calcipotriol (MC 903) is a synthetic VitD3 analogue. Which has a high affinity for the vitamin D receptor.

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Imiquimod hydrochloride

T2209199011-78-6

Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].

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Oxazolone

T509515646-46-5

Oxazolone has been used as a haptenizing agent to induce inflammatory responses in intestinal tissue of adult zebrafish and as a model for gene expression studies in two forms of inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.

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IL-17 Protein, Mouse, Recombinant (His)

TMPJ-01172

Expression system: HEK293 Cells
Length: 22-158, Partial
Activity: BLI、Cells

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Imiquimod

T013499011-02-6

Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.

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DMBA

T3669657-97-6

DMBA (7,12-Dimethylbenz[a]anthracene) induces leukemia, hepatocellular carcinoma, and mammary carcinoma in rats, and programmed cell death (apoptosis) in B-cell lymphomas in A20.1 mice.

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Imiquimod maleate

T22862896106-16-4

Imiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects. Imiquimod maleate induces psoriatic-like skin lesions in mice and can be used to study various skin malignancies.

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Imiquimod 2HCl

T0134L2995277-02-4

Imiquimod 2HCl is a toll-like receptor 7 (TLR7) agonist and an immunomodulator with antiviral and antitumor activity.Imiquimod 2HCl can be used to construct a psoriasis-like mouse model, which can be used to study periocular skin cancers, pemphigus foliaceus, and COVID-19 infection.

$195

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