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Lampalizumab

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Catalog No. T76814Cas No. 1278466-20-8
Alias TNX234, TNX 234, RG7417, RG 7417, Anti-CFD Recombinant Antibody

Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Complement Factor D in the complement pathway, used in age-related macular degeneration (AMD) and cardiovascular disease research.

Lampalizumab

Lampalizumab

😃Good
Catalog No. T76814Alias TNX234, TNX 234, RG7417, RG 7417, Anti-CFD Recombinant AntibodyCas No. 1278466-20-8
Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Complement Factor D in the complement pathway, used in age-related macular degeneration (AMD) and cardiovascular disease research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$263In StockIn Stock
5 mg$795In StockIn Stock
10 mg$1,260-In Stock
25 mg$1,870-In Stock
50 mg$2,520-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.46% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Complement Factor D in the complement pathway, used in age-related macular degeneration (AMD) and cardiovascular disease research.
In vivo
Lampalizumab achieved rapid equilibrium in eye tissue after intravitreal administration in cynomophagus monkeys. Its elimination is relatively slow in the eyes, τ1/2 in about 3 days, while the whole body is quickly eliminated, τ1/2 in 0.8 hours. [1]
SynonymsTNX234, TNX 234, RG7417, RG 7417, Anti-CFD Recombinant Antibody
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetComplement Factor D
Chemical Properties
Molecular Weight143.8 kDa
Cas No.1278466-20-8
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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