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Lampalizumab (Synonyms: TNX234, TNX 234, RG7417, RG 7417, Anti-CFD Recombinant Antibody)

Catalog No. T76814 Copy Product Info
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Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Complement Factor D in the complement pathway, used in age-related macular degeneration (AMD) and cardiovascular disease research.

Lampalizumab

Copy Product Info
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Catalog No. T76814
Synonyms TNX234, TNX 234, RG7417, RG 7417, Anti-CFD Recombinant Antibody

Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Complement Factor D in the complement pathway, used in age-related macular degeneration (AMD) and cardiovascular disease research.

Lampalizumab
Cas No. 1278466-20-8
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$263In StockIn Stock
5 mg$795In StockIn Stock
10 mg$1,260-In Stock
25 mg$1,870-In Stock
50 mg$2,520-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.46% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Complement Factor D in the complement pathway, used in age-related macular degeneration (AMD) and cardiovascular disease research.
In vivo
Lampalizumab achieved rapid equilibrium in eye tissue after intravitreal administration in cynomophagus monkeys. Its elimination is relatively slow in the eyes, τ1/2 in about 3 days, while the whole body is quickly eliminated, τ1/2 in 0.8 hours. [1]
SynonymsTNX234, TNX 234, RG7417, RG 7417, Anti-CFD Recombinant Antibody
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetComplement Factor D
Chemical Properties
Molecular Weight143.8 kDa
Cas No.1278466-20-8
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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