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Ap4A tetraammonium

Name: Ap4A tetraammonium
Brand: TargetMol
SKU: T89481
Rating: 4.5 (1 reviews)

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Catalog No. T89481Cas No. 102783-36-8

Alias P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium

Ap4A tetraammonium, a conserved second messenger across organisms from bacteria to humans, binds and activates the transcription of MITF downstream genes in conjunction with histidine triad nucleotide-binding protein 1 (HINT1). Additionally, Ap4A tetraammonium induces cell apoptosis (apoptosis).

Ap4A tetraammonium

😃Good

Catalog No. T89481Alias P1,P4-Di-(adenosine-5')-tetraphosphate tetraammoniumCas No. 102783-36-8

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Ap4A tetraammonium, a conserved second messenger across organisms from bacteria to humans, binds and activates the transcription of MITF downstream genes in conjunction with histidine triad nucleotide-binding protein 1 (HINT1). Additionally, Ap4A tetraammonium induces cell apoptosis (apoptosis).
In vitro	Ap4A tetraammonium (1, 10 µM; 24 h) induces apoptosis in HL60 cells.
Synonyms	P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium

Chemical Properties

Molecular Weight	904.51
Formula	C₂₀H₄₀N₁₄O₁₉P₄
Cas No.	102783-36-8
Smiles	O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP(OP(OC[C@H]2O[C@@H](N3C4=NC=NC(N)=C4N=C3)[C@@H]([C@@H]2O)O)([O-])=O)([O-])=O)([O-])=O)([O-])=O)N5C6=NC=NC(N)=C6N=C5.[NH4+].[NH4+].[NH4+].[NH4+]

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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