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Ap4A tetraammonium

Name: Ap4A tetraammonium
Brand: TargetMol
SKU: T89481
Rating: 4.5 (1 reviews)

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Catalog No. T89481Cas No. 102783-36-8

Alias P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium

Ap4A tetraammonium, a conserved second messenger across organisms from bacteria to humans, binds and activates the transcription of MITF downstream genes in conjunction with histidine triad nucleotide-binding protein 1 (HINT1). Additionally, Ap4A tetraammonium induces cell apoptosis (apoptosis).

Ap4A tetraammonium

😃Good

Catalog No. T89481Alias P1,P4-Di-(adenosine-5')-tetraphosphate tetraammoniumCas No. 102783-36-8

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	Inquiry	Backorder	Backorder
50 mg	Inquiry	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Ap4A tetraammonium, a conserved second messenger across organisms from bacteria to humans, binds and activates the transcription of MITF downstream genes in conjunction with histidine triad nucleotide-binding protein 1 (HINT1). Additionally, Ap4A tetraammonium induces cell apoptosis (apoptosis).
In vitro	Ap4A tetraammonium (1, 10 µM; 24 h) induces apoptosis in HL60 cells.
Synonyms	P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium

Chemical Properties

Molecular Weight	904.51
Formula	C₂₀H₄₀N₁₄O₁₉P₄
Cas No.	102783-36-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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