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NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00091
Synonyms: 1C7, LY117, CD337, NKp30, MALS, NCR3

NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 814.00
500 μg 5 days $ 3,250.00
1 mg 5 days $ 5,440.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells.
Species Human
Expression System HEK293
Tag C-His-Avi
Accession Number O14931-1
Synonyms 1C7, LY117, CD337, NKp30, MALS, NCR3
Construction Recombinant Biotinylated Human NKp30/NCR3/CD337 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Leu19-Thr138.[Accession |AAH52582]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 20 kDa. Due to glycosylation, the protein migrates to 26-45 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells.

References and Literature

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Keywords

NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated 1C7 LY117 CD-337 NCR-3 CD337 CD 337 NCR 3 NKp30 LY-117 MALS NCR3 LY 117 recombinant recombinant-proteins proteins protein

 

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