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OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

(Synonyms: Tumor necrosis factor ligand 2B, TNFSF4, OX-40L) Copy Product Info

Synonyms: Tumor necrosis factor ligand 2B, TNFSF4, OX-40L

Catalog No. TMPJ-01441 Copy Product Info
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$5535 days35 days
10 μg$8635 days35 days
20 μg$13735 days35 days
50 μg$26235 days35 days
100 μg$48835 days35 days
200 μg$92335 days35 days
500 μg$2,15035 days35 days
1 mg$3,22035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.
Species
Cynomolgus/Rhesus macaque
Expression System
HEK293 Cells
TagN-His
Accession NumberA0A2K5TTN0(Cynomolgus) / A0A1D5QQH7(Rhesus macaque)
ConstructionGln81-Leu213 (Cynomolgus) / Gln51-Leu183 (Rhesus macaque)
Protein Purity
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin<1 EU/µg as determined by LAL test.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsTumor necrosis factor ligand 2B, TNFSF4, OX-40L
Research Background
Chemical Properties
Molecular Weight17.01 kDa (predicted); 25-38 kDa (due to glycosylation); 60-70 kDa (SEC-MALS)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His) chemical structure | OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His) molecular weight