OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)

Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.

Pack Size	Availability	Price/USD
10 μg	5 days	$ 86.00
50 μg	5 days	$ 262.00
500 μg	5 days	$ 2,150.00
1 mg	5 days	$ 3,220.00

Pack Size

Availability

Price/USD

Quantity

10 μg

5 days

$ 86.00

50 μg

5 days

$ 262.00

500 μg

5 days

$ 2,150.00

1 mg

5 days

$ 3,220.00

Description

Species	Cynomolgus
Expression System	HEK293 Cells
Tag	N-8xHis
Accession Number	F7FL80
Synonyms	OX-40L, TNFSF4, Tumor necrosis factor ligand 2B
Amino Acid	Gln51-Leu183
Construction	Gln51-Leu183
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	23-30 Kda (reducing condition)

Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.

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OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)

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