OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Catalog No. TMPJ-01441 Copy Product Info

Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.

OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Catalog No. TMPJ-01441

Copy Product Info

OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$55	2-4 weeks	2-4 weeks
10 μg	$86	2-4 weeks	2-4 weeks
20 μg	$137	2-4 weeks	2-4 weeks
50 μg	$262	2-4 weeks	2-4 weeks
100 μg	$488	2-4 weeks	2-4 weeks
200 μg	$923	2-4 weeks	2-4 weeks
500 μg	$2,150	2-4 weeks	2-4 weeks
1 mg	$3,220	2-4 weeks	2-4 weeks

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Immobilized Cynomolgus/Rhesus macaque OX40 Ligand, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human OX40, hFc Tag with the EC50 of 18.7 ng/ml determined by ELISA.
Description	Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.
Species	Cynomolgus/Rhesus macaque
Expression System	HEK293 Cells
Tag	N-His
Accession Number	A0A2K5TTN0(Cynomolgus) / A0A1D5QQH7(Rhesus macaque)
Synonyms	Tumor necrosis factor ligand 2B,TNFSF4,OX-40L
Construction	Gln81-Leu213 (Cynomolgus) / Gln51-Leu183 (Rhesus macaque)
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Molecular Weight	17.01 kDa (predicted); 25-38 kDa (due to glycosylation); 60-70 kDa (SEC-MALS)
Endotoxin	<1 EU/µg as determined by LAL test.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.