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Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 5 μg | $86 | 20 days | |
| 10 μg | $138 | 20 days | |
| 20 μg | $231 | 20 days | |
| 50 μg | $348 | 20 days | |
| 100 μg | $480 | 20 days | |
| 200 μg | $743 | 20 days | |
| 500 μg | $1,330 | 20 days | 
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.  | 
| Description | Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.  | 
| Species | Human  | 
| Expression System | P. pastoris (Yeast)  | 
| Tag | N-6xHis | 
| Accession Number | P15924 | 
| Synonyms | DSP,DP,Desmoplakin,250/210 kDa paraneoplastic pemphigus antigen  | 
| Amino Acid | CSDCLMRAELIVQPELKYGDGIQLTRSRELDECFAQANDQMEILDSLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLGWMRQQRAEMDMVAWGVDLASVEQHINSHRGIHNSIGDYRWQLDKIKADLREKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSD  | 
| Construction | 78-300 aa  | 
| Protein Purity | > 90% as determined by SDS-PAGE.  | 
| Molecular Weight | 28.1 kDa (predicted) | 
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| Formulation | Tris-based buffer, 50% glycerol | 
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.  | 
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.  | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| Research Background | Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.  | 

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