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Anti-FBXO45 Polyclonal Antibody
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Catalog No. TMAB-00663
Alias hFbxo45, fbxo45, FBX45, FBSP1, F-box/SPRY domain-containing protein 1, F box protein 45
Anti-FBXO45 Polyclonal Antibody is a Rabbit antibody targeting FBXO45. Anti-FBXO45 Polyclonal Antibody can be used in WB.
Anti-FBXO45 Polyclonal Antibody
Anti-FBXO45 Polyclonal Antibody
😃Good
Catalog No. TMAB-00663Alias hFbxo45, fbxo45, FBX45, FBSP1, F-box/SPRY domain-containing protein 1, F box protein 45
Anti-FBXO45 Polyclonal Antibody is a Rabbit antibody targeting FBXO45. Anti-FBXO45 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-FBXO45 Polyclonal Antibody is a Rabbit antibody targeting FBXO45. Anti-FBXO45 Polyclonal Antibody can be used in WB. |
| Alias | hFbxo45, fbxo45, FBX45, FBSP1, F-box/SPRY domain-containing protein 1, F box protein 45 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Sample: Intestine (Mouse) Lysate at 40 μg Primary: Anti-FBXO45 (TMAB-00663) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa 2. Sample: Lane 1: Human A431 cell lysates Lane 2: Human MCF-7 cell lysates Lane 3: Human U251 cell lysates Lane 4: Human K562 cell lysates Lane 5: Human Jurkat cell lysates Primary: Anti-FBXO45 (TMAB-00663) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 30 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction > synapse > postsynaptic cell membrane. Cell junction > synapse > presynaptic cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene. |
| Immunogen | KLH conjugated synthetic peptide: human FBXO45 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID |
| Molecular Weight | Theoretical: 31 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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