Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-FBXO45 Polyclonal Antibody
😃Good
Catalog No. TMAB-00663
Alias hFbxo45, fbxo45, FBX45, FBSP1, F-box/SPRY domain-containing protein 1, F box protein 45
Anti-FBXO45 Polyclonal Antibody is a Rabbit antibody targeting FBXO45. Anti-FBXO45 Polyclonal Antibody can be used in WB.
Anti-FBXO45 Polyclonal Antibody
Anti-FBXO45 Polyclonal Antibody
😃Good
Catalog No. TMAB-00663Alias hFbxo45, fbxo45, FBX45, FBSP1, F-box/SPRY domain-containing protein 1, F box protein 45
Anti-FBXO45 Polyclonal Antibody is a Rabbit antibody targeting FBXO45. Anti-FBXO45 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-FBXO45 Polyclonal Antibody is a Rabbit antibody targeting FBXO45. Anti-FBXO45 Polyclonal Antibody can be used in WB. |
| Synonyms | hFbxo45, fbxo45, FBX45, FBSP1, F-box/SPRY domain-containing protein 1, F box protein 45 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Sample: Intestine (Mouse) Lysate at 40 μg Primary: Anti-FBXO45 (TMAB-00663) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa 2. Sample: Lane 1: Human A431 cell lysates Lane 2: Human MCF-7 cell lysates Lane 3: Human U251 cell lysates Lane 4: Human K562 cell lysates Lane 5: Human Jurkat cell lysates Primary: Anti-FBXO45 (TMAB-00663) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 30 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction > synapse > postsynaptic cell membrane. Cell junction > synapse > presynaptic cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene. |
| Immunogen | KLH conjugated synthetic peptide: human FBXO45 |
| Antigen Species | Human |
| Gene Name | FBXO45 |
| Gene ID | |
| Protein Name | F-box/SPRY domain-containing protein 1 |
| Uniprot ID | |
| Function | Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation. |
| Molecular Weight | Theoretical: 31 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-FBXO45 Polyclonal Antibody | purchase Anti-FBXO45 Polyclonal Antibody | Anti-FBXO45 Polyclonal Antibody cost | order Anti-FBXO45 Polyclonal Antibody | Anti-FBXO45 Polyclonal Antibody molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.