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Anti-IL-9 Antibody (2G981) (Synonyms: P40, interleukin 9, Il-9)
Catalog No. TMAY-03837 Copy Product Info
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Anti-IL-9 Antibody (2G981) is a Mouse antibody targeting IL-9. Anti-IL-9 Antibody (2G981) can be used in ELISA.
Anti-IL-9 Antibody (2G981)
Copy Product Info🥰Excellent
Catalog No. TMAY-03837
Synonyms P40, interleukin 9, Il-9
Anti-IL-9 Antibody (2G981) is a Mouse antibody targeting IL-9. Anti-IL-9 Antibody (2G981) can be used in ELISA.
Anti-IL-9 Antibody
(2G981)
(2G981)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
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| Description | Anti-IL-9 Antibody (2G981) is a Mouse antibody targeting IL-9. Anti-IL-9 Antibody (2G981) can be used in ELISA. |
| Synonyms | P40, interleukin 9, Il-9 |
| Ig Type | Mouse IgG1 |
| Clone | 2G981 |
| Reactivity | Rat |
| Specificity | Rat IL-9 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat IL-9 (rR IL-9; TMPY-00459; NP_001099217.1; Met1-Ala144). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. IL-9 is a key molecule that affects the differentiation of TH17 cells and Treg function. IL-9 predominantly produced by TH17 cells synergizes with TGF-β1 to differentiate naive CD4+ T cells into TH17 cells, while IL-9 secretion by TH17 cells is regulated by IL-23. Interestingly, IL-9 enhances the suppressive functions of FoxP3+ CD4+ Treg cells in vitro, and the absence of IL-9 signaling weakens the suppressive activity of nTregs in vivo, leading to an increase in effector cells and worsening of experimental autoimmune encephalomyelitis. The mechanism of IL-9 effects on TH17 and Tregs is through activation of STAT3 and STAT5 signaling. Our findings highlight the role of IL-9 as a regulator of pathogenic versus protective mechanisms of immune responses. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat IL-9 Protein (TMPY-00459) |
| Antigen Species | Rat |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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