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Datopotamab
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Synonyms:
Catalog No. T9901A-007 Copy Product Info
Purity: 98.10%
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Datopotamab (CDP7657) is a TROP2-targeting antibody that is a naked antibody to Datopotamab deruxtecan and can be used to synthesize active antibody conjugators (Datopotamab deruxtecan). Datopotamab is being investigated for use in triple-negative breast cancer and non-small cell lung cancer.
Cas No. 2267989-53-5
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $255 | - | In Stock | |
| 5 mg | $663 | - | In Stock | |
| 10 mg | Inquiry | - | In Stock | |
| 25 mg | Inquiry | - | In Stock | |
| 50 mg | Inquiry | Inquiry | Inquiry | |
| 100 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
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Purity:98.10%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Datopotamab (CDP7657) is a TROP2-targeting antibody that is a naked antibody to Datopotamab deruxtecan and can be used to synthesize active antibody conjugators (Datopotamab deruxtecan). Datopotamab is being investigated for use in triple-negative breast cancer and non-small cell lung cancer. |
| Targets & IC50 | HGSOC cells (TROP2 3+):0.49 µM |
| Expression System | HEK293 |
| Endotoxin | <1.0 EU/mg |
| Reactivity | Human |
| Verified Activity | Immobilized Human TROP-2 Protein (His) (TMPY-01262) at 1 μg/mL (100 μL/well) can bind Datopotamab. The EC50 is 1.40 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TROP2 |
| Molecular Weight | 145.28 kDa |
| Cas No. | 2267989-53-5 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Datopotamab chemical structure | Datopotamab molecular weight
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