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Anti-CBS Polyclonal Antibody is a Rabbit antibody targeting CBS. Anti-CBS Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-CBS Polyclonal Antibody is a Rabbit antibody targeting CBS. Anti-CBS Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Cow,Rabbit) |
| Verified Activity | 1. Sample: Liver (Mouse) Cell Lysate at 40 μg Primary: Anti-CBS (TMAB-00301) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kDa Observed band size: 61 kDa 2. Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CBS) Polyclonal Antibody, Unconjugated (TMAB-00301) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010]. |
| Immunogen | KLH conjugated synthetic peptide: human HIP4 |
| Antigen Species | Human |
| Gene Name | CBS |
| Gene ID | |
| Protein Name | Cystathionine beta-synthase |
| Uniprot ID | |
| Biology Area | Cellular metabolic process,Amino acid metabolism,Amino Acids |
| Molecular Weight | Theoretical: 61 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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