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Anti-KDM5A Antibody (8P685) (Synonyms: Retinoblastoma-binding protein 2, Retinoblastoma binding protein 2, RBP...)
Catalog No. TMAC-02302 Copy Product Info
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Anti-KDM5A Antibody (8P685) is a Rabbit antibody targeting KDM5A. Anti-KDM5A Antibody (8P685) can be used in FCM,ICC,IF,WB.
Anti-KDM5A Antibody (8P685)
Copy Product Info🥰Excellent
Catalog No. TMAC-02302
Synonyms Retinoblastoma-binding protein 2, Retinoblastoma binding protein 2, RBP2, RBBP-2, RBBP2, Lysine-specific demethylase 5A, KDM5A_HUMAN, Kdm 5a, Jumonji/ARID domain-containing protein 1A, Jumonji/ARID domain containing protein 1A, JARID1A, Histone demethylase JARID1A
Anti-KDM5A Antibody (8P685) is a Rabbit antibody targeting KDM5A. Anti-KDM5A Antibody (8P685) can be used in FCM,ICC,IF,WB.
Anti-KDM5A Antibody
(8P685)
(8P685)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-KDM5A Antibody (8P685) is a Rabbit antibody targeting KDM5A. Anti-KDM5A Antibody (8P685) can be used in FCM,ICC,IF,WB. |
| Synonyms | Retinoblastoma-binding protein 2, Retinoblastoma binding protein 2, RBP2, RBBP-2, RBBP2, Lysine-specific demethylase 5A, KDM5A_HUMAN, Kdm 5a, Jumonji/ARID domain-containing protein 1A, Jumonji/ARID domain containing protein 1A, JARID1A, Histone demethylase JARID1A |
| Ig Type | IgG |
| Clone | 8P685 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of KDM5A on A549 cell using anti-KDM5A antibody at 1/500 dilution. 2. ICC staining KDM5A in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining KDM5A in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of SH-SY-5Y cells with KDM5A antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.     |
| Application | |
| Recommended Dose | WB: 1:500; ICC: 1:50-400; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Regulates specific gene transcription through DNA-binding on 5'-CCGCCC-3' motif. May stimulate transcription mediated by nuclear receptors. Involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1. Seems to act as a transcriptional corepressor for some genes such as MT1F and to favor the proliferation of cancer cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 192 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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