Powder: -20°C for 3 years | In solvent: -80°C for 1 year
pUL89 Endonuclease-IN-1 (Compound 13d), with an IC50 value of 0.88 μM, serves as a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease, demonstrating antiviral activity [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | pUL89 Endonuclease-IN-1 (Compound 13d), with an IC50 value of 0.88 μM, serves as a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease, demonstrating antiviral activity [1]. |
In vitro | pUL89 Endonuclease-IN-1 (compound 13d) effectively suppresses pUL89-C, as evidenced by an IC50 value of 0.88µM. This compound also demonstrates outstanding aqueous solubility, plasma stability, and in vitro ADME metabolic stability. Furthermore, it exhibits moderate permeability according to the PAMPA [1]. In cell cytotoxicity assays [1] using HFF cells at a concentration of 5 µM over 168 hours, pUL89 Endonuclease-IN-1 significantly inhibits HCMV at 5 µM. |
Molecular Weight | 252.25 |
Formula | C10H8N2O4S |
CAS No. | 391680-92-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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pUL89 Endonuclease-IN-1 391680-92-5 inhibitor inhibit