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NLRP3-IN-2

🥰Excellent
Catalog No. T3230Cas No. 16673-34-0
Alias NLRP3 Inflammasome Inhibitor I, 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide

NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.

NLRP3-IN-2

NLRP3-IN-2

🥰Excellent
Purity: 98.98%
Catalog No. T3230Alias NLRP3 Inflammasome Inhibitor I, 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamideCas No. 16673-34-0
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
Pack SizePriceAvailabilityQuantity
25 mg$31In Stock
50 mg$41In Stock
100 mg$53In Stock
500 mg$123In Stock
1 g$179In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:98.98%
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Product Introduction

Bioactivity
Description
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
SynonymsNLRP3 Inflammasome Inhibitor I, 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide
Chemical Properties
Molecular Weight368.84
FormulaC16H17ClN2O4S
Cas No.16673-34-0
SmilesCOc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O
Relative Density.1.356g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (149.12 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7112 mL13.5560 mL27.1120 mL135.5601 mL
5 mM0.5422 mL2.7112 mL5.4224 mL27.1120 mL
10 mM0.2711 mL1.3556 mL2.7112 mL13.5560 mL
20 mM0.1356 mL0.6778 mL1.3556 mL6.7780 mL
50 mM0.0542 mL0.2711 mL0.5422 mL2.7112 mL
100 mM0.0271 mL0.1356 mL0.2711 mL1.3556 mL

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Keywords

reperfusionNODlikeReceptor(NLR)NODlikeReceptorNOD-like Receptor (NLR)NODlike Receptor (NLR)NOD-like ReceptorNLRP3-IN-2NLRP-3-IN-2NLRP3IN2NLRP3 IN 2NLRP3NLRmyocardialischemiaInhibitorinhibitinflammasomeinfarctionacute
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