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IL-12 Protein, Mouse, Recombinant

(Synonyms: TSF, TCMF, NKSF, IL12, Cytotoxic lymphocyte maturation factor, CTL maturation factor, CLMF) Copy Product Info

Synonyms: TSF, TCMF, NKSF, IL12, Cytotoxic lymphocyte maturation factor, CTL maturation factor, CLMF

Catalog No. TMPS-00064 Copy Product Info
IL-12 Protein, Mouse, Recombinant is expressed in CHO Cells. The accession number is P43431.
IL-12 Protein, Mouse, Recombinant
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$2127-10 days7-10 days
10 μg$3537-10 days7-10 days
20 μg$5487-10 days7-10 days
50 μg$9877-10 days7-10 days
100 μg$1,5607-10 days7-10 days
200 μg$2,4707-10 days7-10 days
500 μg$4,5507-10 days7-10 days
1 mg$7,2307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
ED 50 < 0.15 ng/ml, measured in a cell proliferation assay using 2D6 cells.
Description
IL-12 Protein, Mouse, Recombinant is expressed in CHO Cells. The accession number is P43431.
Species
Mouse
Expression System
CHO Cells
TagTag Free
Accession NumberP43431
ConstructionArg23-Ser215
Protein Purity
> 95% as determined by SDS-PAGE
Endotoxin< 0.2 EU/μg of protein as determined by the LAL method.
FormulationLyophilized from a 0.2 μm filtered solution in PBS.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageUpon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsTSF, TCMF, NKSF, IL12, Cytotoxic lymphocyte maturation factor, CTL maturation factor, CLMF
Research Background
Interleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes, macrophages, B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex, which is comprised of IL-12 Rβ1 and IL-12 Rβ2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells and T- cells. It is indispensible during the development of Th1 cells, leading to the production of IFN-gamma and IL-2.
Chemical Properties
Molecular Weight27~29 kDa (p35), 45~50 kDa (p40) (Reducing conditions)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: IL-12 Protein, Mouse, Recombinant chemical structure | IL-12 Protein, Mouse, Recombinant molecular weight