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Anti-PCSK9 Antibody (5X919) (Synonyms: proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LD...)
Catalog No. TMAY-03672 Copy Product Info
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Anti-PCSK9 Antibody (5X919) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (5X919) can be used in IHC-P.
Anti-PCSK9 Antibody (5X919)
Copy Product Info🥰Excellent
Catalog No. TMAY-03672
Synonyms proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3
Anti-PCSK9 Antibody (5X919) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (5X919) can be used in IHC-P.
Anti-PCSK9 Antibody
(5X919)
(5X919)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PCSK9 Antibody (5X919) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (5X919) can be used in IHC-P. |
| Synonyms | proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3 |
| Ig Type | Mouse IgG1 |
| Clone | 5X919 |
| Reactivity | Rat |
| Specificity | Rat PCSK9 No cross-reactivity in ELISA with Human PCSK9 Rhesus PCSK9 |
| Verified Activity | Immunochemical staining of rat PCSK9 in rat brain with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat PCSK9 (rR PCSK9; TMPY-01565; NP_954862.2; Met1-Gln691). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat PCSK9 protein (TMPY-01565) |
| Antigen Species | Rat |
| Biology Area | Serine Proteases and Regulators |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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