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(S,R,S)-AHPC-Me-C10-Br

🥰Excellent
Catalog No. T18668Cas No. 2836297-55-1

(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate and ligand-linker for E3 ligase, consisting of MS432 for MEK1/2 inhibitors and a VHL E3 ligase linker.

(S,R,S)-AHPC-Me-C10-Br

(S,R,S)-AHPC-Me-C10-Br

🥰Excellent
Purity: 98.89%
Catalog No. T18668Cas No. 2836297-55-1
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate and ligand-linker for E3 ligase, consisting of MS432 for MEK1/2 inhibitors and a VHL E3 ligase linker.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30-In Stock
5 mg$67-In Stock
10 mg$98-In Stock
25 mg$198-In Stock
50 mg$328-In Stock
100 mg$529-In Stock
1 mL x 10 mM (in DMSO)$108-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.89%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate and ligand-linker for E3 ligase, consisting of MS432 for MEK1/2 inhibitors and a VHL E3 ligase linker.
Chemical Properties
Molecular Weight691.76
FormulaC34H51BrN4O4S
Cas No.2836297-55-1
SmilesC([C@@H](NC(CCCCCCCCCCBr)=O)[C@@](C)(C)C)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (115.65 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4456 mL7.2279 mL14.4559 mL72.2794 mL
5 mM0.2891 mL1.4456 mL2.8912 mL14.4559 mL
10 mM0.1446 mL0.7228 mL1.4456 mL7.2279 mL
20 mM0.0723 mL0.3614 mL0.7228 mL3.6140 mL
50 mM0.0289 mL0.1446 mL0.2891 mL1.4456 mL
100 mM0.0145 mL0.0723 mL0.1446 mL0.7228 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

AHPC-Me-C10-Br(S,R,S)-AHPC-Me-C-10-Br(S,R,S)AHPCMeC10Br(S,R,S) AHPC Me C10 Br
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