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(S,R,S)-AHPC-Me-C10-Br

Name: (S,R,S)-AHPC-Me-C10-Br
Brand: TargetMol
SKU: T18668
Price: 57 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18668Cas No. 2836297-55-1

(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate and ligand-linker for E3 ligase, consisting of MS432 for MEK1/2 inhibitors and a VHL E3 ligase linker.

(S,R,S)-AHPC-Me-C10-Br

🥰Excellent

Purity: 98.89%

Catalog No. T18668Cas No. 2836297-55-1

(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate and ligand-linker for E3 ligase, consisting of MS432 for MEK1/2 inhibitors and a VHL E3 ligase linker.

Pack Size	Price	Availability
1 mg	$57	In Stock
5 mg	$129	In Stock
10 mg	$192	In Stock
25 mg	$319	In Stock
50 mg	$477	In Stock
100 mg	$697	In Stock
200 mg	$993	In Stock

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Purity:98.89%

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COA LCMS HNMR

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Product Introduction

Bioactivity

Description

(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate and ligand-linker for E3 ligase, consisting of MS432 for MEK1/2 inhibitors and a VHL E3 ligase linker.

Chemical Properties

Molecular Weight	691.76
Formula	C₃₄H₅₁BrN₄O₄S
Cas No.	2836297-55-1
Smiles	C([C@@H](NC(CCCCCCCCCCBr)=O)[C@@](C)(C)C)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (115.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4456 mL	7.2279 mL	14.4559 mL	72.2794 mL
5 mM	0.2891 mL	1.4456 mL	2.8912 mL	14.4559 mL
10 mM	0.1446 mL	0.7228 mL	1.4456 mL	7.2279 mL
20 mM	0.0723 mL	0.3614 mL	0.7228 mL	3.6140 mL
50 mM	0.0289 mL	0.1446 mL	0.2891 mL	1.4456 mL
100 mM	0.0145 mL	0.0723 mL	0.1446 mL	0.7228 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc