Topoisomerase IV inhibitor 2

Name: Topoisomerase IV inhibitor 2
Brand: TargetMol
SKU: T72154
Rating: 4.5 (1 reviews)

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Catalog No. T72154Cas No. 2883403-36-7

Topoisomerase IV inhibitor 2 (compound 5d) is an effective Topo IV inhibitor with IC50 values of 0.35 μM and 0.55 μM for Topo IV and DNA cyclase, respectively, and has antibacterial activity.

Topoisomerase IV inhibitor 2

😃Good

Catalog No. T72154Cas No. 2883403-36-7

Topoisomerase IV inhibitor 2 (compound 5d) is an effective Topo IV inhibitor with IC50 values of 0.35 μM and 0.55 μM for Topo IV and DNA cyclase, respectively, and has antibacterial activity.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Topoisomerase IV inhibitor 2 (compound 5d) is an effective Topo IV inhibitor with IC50 values of 0.35 μM and 0.55 μM for Topo IV and DNA cyclase, respectively, and has antibacterial activity.
Targets&IC50	Topo IV:0.35 μM

Chemical Properties

Molecular Weight	671.7
Formula	C₃₃H₃₀FN₇O₆S
Cas No.	2883403-36-7
Smiles	C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCN(CC4)CC(=O)NC5=CC=C(C=C5)S(=O)(=O)NC6=NC7=CC=CC=C7N=C6)F)C(=O)O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc