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Anti-HGFR/c-Met Antibody-PE (4V580)
🥰Excellent
Catalog No. TMAY-01071P
Anti-HGFR/c-Met Antibody-PE (4V580) is a PE-conjugated Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody-PE (4V580) can be used in FCM.
Anti-HGFR/c-Met Antibody-PE (4V580)
Anti-HGFR/c-Met Antibody-PE (4V580)
🥰Excellent
Catalog No. TMAY-01071P
Anti-HGFR/c-Met Antibody-PE (4V580) is a PE-conjugated Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody-PE (4V580) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-HGFR/c-Met Antibody-PE (4V580) is a PE-conjugated Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody-PE (4V580) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4V580 |
| Reactivity | Human |
| Verified Activity | Profile of anti-human C-Met (HGF R) reactivity on HepG2 cells analyzed by flow cytometry. The Clone 4V580 and 6L502 monoclonal antibodies are not cross-blocking. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human HGFR / c-MET (rh HGFR / c-MET; TMPY-01296; NP_000236.2; Met 1-Thr 932) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human HGFR / c-MET protein (TMPY-01296) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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