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Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 19.5 kDa and the accession number is Q9JKV9.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $51 | 7-10 days | 7-10 days | |
| 10 μg | $80 | 7-10 days | 7-10 days | |
| 20 μg | $129 | 7-10 days | 7-10 days | |
| 50 μg | $248 | 7-10 days | 7-10 days | |
| 100 μg | $418 | In Stock | In Stock | |
| 200 μg | $757 | 7-10 days | 7-10 days | |
| 500 μg | $1,670 | 7-10 days | 7-10 days |
| Biological Activity | Mouse IL-20RA, hFc Tag captured on CM5 Chip via Protein A can bind Mouse IL-20, His Tag with an affinity constant of 14.26 μM as determined in SPR assay. |
| Description | Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 19.5 kDa and the accession number is Q9JKV9. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | N-His |
| Accession Number | Q9JKV9 |
| Synonyms | Zcyto10,MGC96907,IL-20,IL10D,Cytokine Zcyto10 |
| Construction | Leu25- Leu176 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Molecular Weight | 19.5 kDa (predicted). Due to glycosylation, the protein migrates to 20-22 kDa based on Tris-Bis PAGE result. |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl (pH 8.0). |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. |
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