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C-Reactive Protein /CRP Protein, Human, Recombinant (His)

(Synonyms: PTX1MGC149895, PTX1, pentraxin 1, MGC88244, CRP, C-reactive protein) Copy Product Info

Synonyms: PTX1MGC149895, PTX1, pentraxin 1, MGC88244, CRP, C-reactive protein

Catalog No. TMPK-00114 Copy Product Info
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactive Protein /CRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.1 kDa and the accession number is P02741-1.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$39-In Stock
20 µg$59-In Stock
50 µg$109-In Stock
100 µg$178In StockIn Stock
200 µg$3237-10 days7-10 days
500 µg$7267-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactive Protein /CRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.1 kDa and the accession number is P02741-1.
Species
Human
Expression System
HEK293 Cells
TagN-His
Accession NumberP02741-1
ConstructionGln19-Pro224
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
C-Reactive Protein /CRP Protein, Human, Recombinant (His),C-Reactive Protein /CRP Protein, Human, Recombinant (His)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 300 mM NaCl (pH 8.0). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsPTX1MGC149895, PTX1, pentraxin 1, MGC88244, CRP, C-reactive protein
Research Background
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry.
Chemical Properties
Molecular Weight24.1 kDa (predicted). Due to glycosylation, the protein migrates to 25-27 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: C-Reactive Protein /CRP Protein, Human, Recombinant (His) chemical structure | C-Reactive Protein /CRP Protein, Human, Recombinant (His) molecular weight