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TargetMol | Compound Library

DNA Damage & Repair Compound Library

Catalog No. L3900

A significant barrier to effective cancer therapy is the development of resistance to the drugs utilized, therefore, identifying new biological targets and designing new drugs becomes one of the most important strategies. Among the various potential targets, DNA damage and repair system in cancer cells is one of the most pivotal targets. The use of unspecific antibiotics to treat bacterial infections has caused a great deal of multiple resistant strains making less effective the current therapies with antibiotics. Developing inhibitors of DNA repair and related pathways in pathogens will have utility in the treatment of infections.

The TargetMol's DNA Damage & Repair Compound Library, a unique collection of 1440 DNA Damage & Repair related compounds, can be used for research in DNA damage and repair, and high throughput screening (HTS) and high content screening (HCS).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3900

DNA Damage & Repair Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1440 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

DNA/RNA Synthesis
Apoptosis
PPAR
HDAC
Nucleoside Antimetabolite/Analog
PARP
Topoisomerase
Autophagy
Antibacterial
Endogenous Metabolite
Antibiotic
Sirtuin
DUB
NF-κB
Caspase
ROS
Parasite
PI3K
Virus Protease
DNA-PK
ATM/ATR
DNA Alkylator/Crosslinker
Akt
HIV Protease
mTOR
DHFR
Dehydrogenase
Influenza Virus
DNA
COX
AMPK
Antifungal
Reactive Oxygen Species
HSV
Bcl-2 Family
p38 MAPK
Interleukin
Wnt/beta-catenin
DNA Alkylation
STAT
SARS-CoV
ERK
Antifolate
Telomerase
MDM-2/p53
Antiviral
JNK
TNF
CDK
DNA gyrase
Mitophagy
Ferroptosis
Cytochromes P450
HCV Protease
Nrf2
ADC Cytotoxin
PKC
p53
HBV
Prostaglandin Receptor
Epigenetic Reader Domain
TGF-beta/Smad
Mitochondrial Metabolism
IL Receptor
MMP
Potassium Channel
Antioxidant
Adenosine Receptor
Reverse Transcriptase
GABA Receptor
PDE
NO Synthase
CRISPR/Cas9
Drug Metabolite
Tyrosinase
JAK
Ras
Antifection
Anti-infection
Phosphatase
Calcium Channel
HSP
AChR
HIF/HIF Prolyl-Hydroxylase
EGFR
BMI-1
DNA Methyltransferase
Pyroptosis
PKA
Gamma-secretase
Lipoxygenase
Microtubule Associated
TRP/TRPV Channel
transporter
MEK
P-gp
TLR
GSK-3
IκB/IKK
MAPK
Sodium Channel
Bcr-Abl
Adrenergic Receptor
Beta Amyloid
FLT
NOD-like Receptor (NLR)
Monoamine Oxidase
RAAS
Glucosidase
MicroRNA
VEGFR
MTH1
KLF
Src
ABC Transporter
IGF-1R
GPCR
c-Myc
Histone Acetyltransferase
Raf
CaMK
Glutathione Peroxidase
Cysteine Protease
Leukotriene Receptor
OXPHOS
LRRK2
Cannabinoid Receptor
Proteasome
Hedgehog/Smoothened
Phospholipase
Cell Cycle Arrest
Immunology/Inflammation related
Angiotensin-converting Enzyme (ACE)
Syk
PROTACs
Carbonic Anhydrase
Histone Demethylase
Tyrosine Kinases
glycosidase
cGAS
Casein Kinase
ribosome
NOD
Histone Methyltransferase
Fatty Acid Synthase
Aurora Kinase
FAK
Transferase
NUDIX hydrolase
IFNAR
Necroptosis
IDO
5-HT Receptor
S6 Kinase
Thrombin
NOS
Serine/threonin kinase
FXR
FABP
LDL
Free radical scavengers
Acetyl-CoA Carboxylase
Retinoid Receptor
Integrin
Reductase
Histamine Receptor
FLAP
Liposome
PAFR
Chk
PI4K
PLK
ATPase
PERK
IAP
E1/E2/E3 Enzyme
Cholinesterase (ChE)
Mdm2
Arginase
c-Met/HGFR
PAK
ALK
Carboxypeptidase
ROS Kinase
PD-1/PD-L1
Androgen Receptor
Indoleamine 2,3-Dioxygenase (IDO)
PGE Synthase
Aminopeptidase
Methionine Adenosyltransferase (MAT)
HMG-CoA Reductase
Kras
YAP
BACE
NADPH
OCT
Bcl-6
ROCK
Molecular Glues
Lipid
PDK
SGK
c-Kit
Proton pump
MyD88
Aryl Hydrocarbon Receptor
Prolyl Endopeptidase (PREP)
PTEN
Xanthine Oxidase
Epoxide Hydrolase
Huntingtin
STING
MLK
Estrogen Receptor/ERR
Beta-Secretase
Adenosine Deaminase
c-RET
TAM Receptor
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
P2Y Receptor
Serine Protease
Glucokinase
NMDAR
Orphan Receptor
Trk receptor
GPCR19
RSV
c-Fms
VDAC
ATG
iGluR
Monoamine Transporter
PDGFR
FAAH
CCR
GluR
Hydroxylase
Sigma receptor
CFTR
HER
gp120/CD4
GTPase
Photosensitizer
MAO
cAMP
Ephrin Receptor
CPT
Aromatase
HIF
Platelet aggregation
Dopamine Receptor
Estrogen/progestogen Receptor
MRP
Adenylate cyclase
UGT
P2X Receptor
PAD
Survivin
Drug-Linker Conjugates for ADC

Keywords