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TargetMol | Compound Library

DNA Damage & Repair Compound Library

Catalog No. L3900

A significant barrier to effective cancer therapy is the development of resistance to the drugs utilized, therefore, identifying new biological targets and designing new drugs becomes one of the most important strategies. Among the various potential targets, DNA damage and repair system in cancer cells is one of the most pivotal targets. The use of unspecific antibiotics to treat bacterial infections has caused a great deal of multiple resistant strains making less effective the current therapies with antibiotics. Developing inhibitors of DNA repair and related pathways in pathogens will have utility in the treatment of infections.

The TargetMol's DNA Damage & Repair Compound Library, a unique collection of 1040 DNA Damage & Repair related compounds, can be used for research in DNA damage and repair, and high throughput screening (HTS) and high content screening (HCS).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3900

DNA Damage & Repair Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1040 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

DNA/RNA Synthesis
Apoptosis
PPAR
HDAC
Topoisomerase
Autophagy
Nucleoside Antimetabolite/Analog
PARP
Antibacterial
Antibiotic
Endogenous Metabolite
Sirtuin
DUB
Virus Protease
DNA-PK
PI3K
ATM/ATR
Parasite
DNA
NF-κB
DNA Alkylator/Crosslinker
DHFR
HIV Protease
Caspase
mTOR
Influenza Virus
DNA Alkylation
Dehydrogenase
HSV
COX
Telomerase
Antifungal
Wnt/beta-catenin
Antifolate
DNA gyrase
Reactive Oxygen Species
SARS-CoV
Bcl-2 Family
Mitophagy
MDM-2/p53
ADC Cytotoxin
Ferroptosis
p38 MAPK
AMPK
p53
HCV Protease
Cytochromes P450
Interleukin
Akt
TNF
Potassium Channel
PDE
CRISPR/Cas9
GABA Receptor
HBV
CDK
Drug Metabolite
Epigenetic Reader Domain
Lipoxygenase
Prostaglandin Receptor
Reverse Transcriptase
STAT
Tyrosinase
Adenosine Receptor
JNK
PKC
EGFR
Antiviral
HSP
Anti-infection
BMI-1
DNA Methyltransferase
MicroRNA
Phosphatase
c-Myc
PKA
TRP/TRPV Channel
ERK
Bcr-Abl
MTH1
Gamma-secretase
Antifection
IL Receptor
MMP
TGF-beta/Smad
Nrf2
KLF
AChR
FLT
HIF/HIF Prolyl-Hydroxylase
NO Synthase
GPCR
Carbonic Anhydrase
Antioxidant
VEGFR
Calcium Channel
LDL
ABC Transporter
Glucosidase
JAK
transporter
IκB/IKK
Beta Amyloid
Cannabinoid Receptor
Sodium Channel
Microtubule Associated
Proteasome
Mdm2
ATPase
PROTACs
Transferase
Src
Arginase
c-Met/HGFR
RAAS
Glutathione Peroxidase
Tyrosine Kinases
Cysteine Protease
Leukotriene Receptor
Adrenergic Receptor
IDO
IAP
Immunology/Inflammation related
Mitochondrial Metabolism
Fatty Acid Synthase
PAK
IGF-1R
Indoleamine 2,3-Dioxygenase (IDO)
OXPHOS
MAPK
P-gp
TLR
Free radical scavengers
Aminopeptidase
Histone Acetyltransferase
cGAS
Casein Kinase
Methionine Adenosyltransferase (MAT)
Carboxypeptidase
Retinoid Receptor
PI4K
Phospholipase
MEK
Syk
Thrombin
Monoamine Oxidase
Proton pump
Dopamine Receptor
Histone Methyltransferase
Integrin
MyD88
Amino Acids and Derivatives
Estrogen/progestogen Receptor
P2Y Receptor
Reductase
Histone Demethylase
NADPH
Histamine Receptor
Necroptosis
OCT
Bcl-6
Serine Protease
Serine/threonin kinase
FXR
Glucokinase
ROCK
MAO
FLAP
E1/E2/E3 Enzyme
UGT
PAFR
P2X Receptor
NMDAR
ROS
Molecular Glues
Hedgehog/Smoothened
PDGFR
FAAH
CCR
Cholinesterase (ChE)
Angiotensin-converting Enzyme (ACE)
Chk
PAD
Aurora Kinase
Androgen Receptor
Lipid
LRRK2
Trk receptor
RSV
c-Fms
Aromatase
ribosome
5-HT Receptor
PLK
c-RET
SGK
c-Kit
NOD
TAM Receptor
FAK
Liposome
NOD-like Receptor (NLR)
CFTR
MLK
HER

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