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ACE2/ACEH Protein, Human, Recombinant (hFc)

(Synonyms: angiotensin I converting enzyme 2, ACEH) Copy Product Info

Synonyms: angiotensin I converting enzyme 2, ACEH

Catalog No. TMPY-00655 Copy Product Info
ACE2/ACEH Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q9BYF1.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$2577-10 days7-10 days
20 µg$4387-10 days7-10 days
50 µg$7377-10 days7-10 days
100 µg$1,2807-10 days7-10 days
200 µg$1,7007-10 days7-10 days
500 µg$3,1307-10 days7-10 days
1 mg$5,6807-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized 2019-nCoV S-trimer Protein-His(Cat#DRA107) at 2μg/ml (100 μl/well) can bind Human ACE-2-Fc(Cat#C05Y). The ED50 of Human ACE-2-Fc(Cat#C05Y) is 23.83 ng/ml. (Regularly tested)
Description
ACE2/ACEH Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q9BYF1.
Species
Human
Expression System
HEK293 Cells
TagC-Fc
Accession NumberQ9BYF1
ConstructionGln18-Ser740
Protein Purity
> 95% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM Tris–HCl, 300 mM NaCl, 10% Glycerol, 100 mM Glycine, pH7.4.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonymsangiotensin I converting enzyme 2, ACEH
Research Background
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Chemical Properties
Molecular Weight110.5 kDa (Predicted); 110-140 kDa (Reducing conditions)
Storage & Solubility Information
ShippingSolutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: ACE2/ACEH Protein, Human, Recombinant (hFc) chemical structure | ACE2/ACEH Protein, Human, Recombinant (hFc) molecular weight