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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-propargyl-PEG12 is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras] that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together, with one ligand binding to an E3 ubiquitin ligase and the other to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs enable the selective degradation of target proteins[1]. |
Molecular Weight | 622.74 |
Formula | C30H54O13 |
Cas No. | 1351373-50-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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