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Anti-Phospho-AMPKα (S496) Antibody (3X970)
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Catalog No. TMAC-03190
Anti-Phospho-AMPKα (S496) Antibody (3X970) is a Rabbit antibody targeting Phospho-AMPKα (S496). Anti-Phospho-AMPKα (S496) Antibody (3X970) can be used in WB,ICC/IF,IP.
Anti-Phospho-AMPKα (S496) Antibody (3X970)
Anti-Phospho-AMPKα (S496) Antibody (3X970)
😃Good
Catalog No. TMAC-03190
Anti-Phospho-AMPKα (S496) Antibody (3X970) is a Rabbit antibody targeting Phospho-AMPKα (S496). Anti-Phospho-AMPKα (S496) Antibody (3X970) can be used in WB,ICC/IF,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Phospho-AMPKα (S496) Antibody (3X970) is a Rabbit antibody targeting Phospho-AMPKα (S496). Anti-Phospho-AMPKα (S496) Antibody (3X970) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | AMPK (5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming bio-synthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. AMPKα1 (5'-AMP-activated protein kinase catalytic subunit alpha-1), also known as PRKAA1, is a 559 amino acid protein that belongs to the CAMK Ser/Thr protein kinase family and protein kinase superfamily. Highly phosphorylated, AMPKα1 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 5p13.1. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human AMPK alpha 1 around the phosphorylation site of Ser496 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 64 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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