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Anti-Phospho-AMPKα (S496) Antibody (3X970)

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Catalog No. TMAC-03190

Anti-Phospho-AMPKα (S496) Antibody (3X970) is a Rabbit antibody targeting Phospho-AMPKα (S496). Anti-Phospho-AMPKα (S496) Antibody (3X970) can be used in WB,ICC/IF,IP.

Anti-Phospho-AMPKα (S496) Antibody (3X970)

Anti-Phospho-AMPKα (S496) Antibody (3X970)

😃Good
Catalog No. TMAC-03190
Anti-Phospho-AMPKα (S496) Antibody (3X970) is a Rabbit antibody targeting Phospho-AMPKα (S496). Anti-Phospho-AMPKα (S496) Antibody (3X970) can be used in WB,ICC/IF,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-AMPKα (S496) Antibody (3X970) is a Rabbit antibody targeting Phospho-AMPKα (S496). Anti-Phospho-AMPKα (S496) Antibody (3X970) can be used in WB,ICC/IF,IP.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAMPK (5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming bio-synthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. AMPKα1 (5'-AMP-activated protein kinase catalytic subunit alpha-1), also known as PRKAA1, is a 559 amino acid protein that belongs to the CAMK Ser/Thr protein kinase family and protein kinase superfamily. Highly phosphorylated, AMPKα1 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 5p13.1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human AMPK alpha 1 around the phosphorylation site of Ser496
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 64 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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