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Mipasetamab
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Catalog No. T77085 Copy Product Info
Purity: 95%
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Mipasetamab is a humanized antibody targeting AXL, a tyrosine kinase receptor or TAM receptor, used in synthetic ADC drugs (e.g., ADCT-601).
Cas No. 2361055-48-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | - | In Stock | |
| 5 mg | $993 | - | In Stock | |
| 10 mg | $1,570 | - | In Stock | |
| 25 mg | $2,330 | - | In Stock | |
| 50 mg | $3,130 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Mipasetamab is a humanized antibody targeting AXL, a tyrosine kinase receptor or TAM receptor, used in synthetic ADC drugs (e.g., ADCT-601). |
| In vitro | ADCT-601 (Mipasetamab uzoptirine) (0.02–9.29 nM; 5 days) exhibits cytotoxicity against AXL-positive SN12C cells and AXL-negative Karpas-299 cells [1]. |
| In vivo | ADCT-601 (Mipasetamab uzoptirine) (1 mg/kg; intravenous injection; once daily for 60 days) demonstrated antitumor activity in mice in both the MDA-MB-231 triple-negative breast cancer (TNBC) xenograft model and the SN12C renal cell carcinoma xenograft model [1]. ADCT-601 (Mipasetamab uzoptirine) (0.075, 0.15, or 0.3 mg/kg; intravenous injection; once daily for 45 days) exhibited dose-dependent activity in a heterogeneous AXL-expressing pancreatic cancer PDX model (PAXF1657) [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | AXL |
| Cas No. | 2361055-48-1 |
| Isotype | IgG1 |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Mipasetamab chemical structure | Mipasetamab in vivo | Mipasetamab in vitro
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