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Mipasetamab
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Catalog No. T77085Cas No. 2361055-48-1
Mipasetamab is a humanized antibody targeting AXL, a tyrosine kinase receptor or TAM receptor, used in synthetic ADC drugs (e.g., ADCT-601).
Mipasetamab
Mipasetamab
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Purity: 95%
Catalog No. T77085Cas No. 2361055-48-1
Mipasetamab is a humanized antibody targeting AXL, a tyrosine kinase receptor or TAM receptor, used in synthetic ADC drugs (e.g., ADCT-601).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | - | In Stock | |
| 5 mg | $993 | - | In Stock | |
| 10 mg | $1,570 | - | In Stock | |
| 25 mg | $2,330 | - | In Stock | |
| 50 mg | $3,130 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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| Description | Mipasetamab is a humanized antibody targeting AXL, a tyrosine kinase receptor or TAM receptor, used in synthetic ADC drugs (e.g., ADCT-601). |
| In vitro | ADCT-601 (Mipasetamab uzoptirine) (0.02–9.29 nM; 5 days) exhibits cytotoxicity against AXL-positive SN12C cells and AXL-negative Karpas-299 cells [1]. |
| In vivo | ADCT-601 (Mipasetamab uzoptirine) (1 mg/kg; intravenous injection; once daily for 60 days) demonstrated antitumor activity in mice in both the MDA-MB-231 triple-negative breast cancer (TNBC) xenograft model and the SN12C renal cell carcinoma xenograft model [1]. ADCT-601 (Mipasetamab uzoptirine) (0.075, 0.15, or 0.3 mg/kg; intravenous injection; once daily for 45 days) exhibited dose-dependent activity in a heterogeneous AXL-expressing pancreatic cancer PDX model (PAXF1657) [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | AXL |
| Cas No. | 2361055-48-1 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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