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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide

🥰Excellent
Catalog No. T9679Cas No. 312508-42-2

N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide exhibit an inhibitory effect on bacterial DNA helicases, nucleases, or helicase-nuclease enzyme complexes, such as, for example, one or more enzymes selected from the RecBCD and AddAB families of enzymes.

N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide

N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide

🥰Excellent
Purity: 99.8%
Catalog No. T9679Cas No. 312508-42-2
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide exhibit an inhibitory effect on bacterial DNA helicases, nucleases, or helicase-nuclease enzyme complexes, such as, for example, one or more enzymes selected from the RecBCD and AddAB families of enzymes.
Pack SizePriceAvailabilityQuantity
1 mg$68In Stock
5 mg$163In Stock
10 mg$238In Stock
25 mg$395In Stock
50 mg$572In Stock
100 mg$768In Stock
200 mg$1,030In Stock
1 mL x 10 mM (in DMSO)$148In Stock
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Purity:99.8%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide exhibit an inhibitory effect on bacterial DNA helicases, nucleases, or helicase-nuclease enzyme complexes, such as, for example, one or more enzymes selected from the RecBCD and AddAB families of enzymes.
Chemical Properties
Molecular Weight284.34
FormulaC14H12N4OS
Cas No.312508-42-2
SmilesC(#N)C=1C2=C(SC1NC(=O)C=3C=NC=CN3)CCCC2
Relative Density.1.40 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (175.85 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5169 mL17.5846 mL35.1692 mL175.8458 mL
5 mM0.7034 mL3.5169 mL7.0338 mL35.1692 mL
10 mM0.3517 mL1.7585 mL3.5169 mL17.5846 mL
20 mM0.1758 mL0.8792 mL1.7585 mL8.7923 mL
50 mM0.0703 mL0.3517 mL0.7034 mL3.5169 mL
100 mM0.0352 mL0.1758 mL0.3517 mL1.7585 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

N(3cyano4,5,6,7tetrahydro1benzothiophen2yl)pyrazine2carboxamideN (3 cyano 4,5,6,7 tetrahydro 1 benzothiophen 2 yl)pyrazine 2 carboxamideAntibacterial
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