B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | In stock | $ 511.00 | |
500 μg | 5 days | $ 2,040.00 | |
1 mg | 5 days | $ 3,410.00 |
Biological Information | 1. Immobilized Human BAFF Trimer, His Tag at 1μg/ml (100μl/well). Dose response curve for Human BAFFR, hFc Tag with the EC50 of 37.8ng/ml determined by ELISA. 2. Human BAFF Trimer, His Tag captured on CM5 Chip via Anti-His Antibody can bind Mouse BCMA, hFc Tag with an affinity constant of 6.59 nM as determined in SPR assay. |
Description | B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. |
Species | Human |
Expression System | HEK293 |
Tag | N-His-Flag |
Accession Number | Q9Y275-1 |
Synonyms | BLyS, TALL-1, TNFSF13B, DTL, TNFSF20, TALL-1δ BAFF, TALL-1delta BAFF, TALL1δ4 BAFF, ZTNF4, TALL1, THANK, BAFF, TALL1Delta4 BAFF, CD257 |
Construction | Recombinant Human BAFF/TNFSF13B/CD257 Trimer Protein is expressed from HEK293 with His tag and Flag tag at the N-Terminus. It contains Thr141-Leu285.[Accession |Q9Y275-1] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. |
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Please read the User Guide of Recombinant Proteins for more specific information.
BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) BLyS TALL 1 TALL-1 TNFSF13B ZTNF-4 DTL TNFSF20 ZTNF 4 TALL-1δ BAFF TALL-1delta BAFF TALL1δ4 BAFF CD 257 TNFSF-20 ZTNF4 TALL1 CD-257 THANK BAFF TALL-1Δ BAFF TNFSF 20 TALL1Delta4 BAFF CD257 recombinant recombinant-proteins proteins protein