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Padsevonil

Name: Padsevonil
Brand: TargetMol
SKU: T16427
Price: 249 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T16427Cas No. 1294000-61-5

Alias UCB1415943-000, UCB-0942

Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.

Padsevonil

🥰Excellent

Purity: 99.63%

Catalog No. T16427Alias UCB1415943-000, UCB-0942Cas No. 1294000-61-5

Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.

Pack Size	Price	Availability	Quantity
1 mg	$249	In Stock

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Batch Information

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Purity:99.63%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.
Synonyms	UCB1415943-000, UCB-0942

Chemical Properties

Molecular Weight	432.80
Formula	C₁₄H₁₄ClF₅N₄O₂S
Cas No.	1294000-61-5
Smiles	COCc1nn2c(CN3C[C@@H](CC(F)(F)Cl)CC3=O)c(nc2s1)C(F)(F)F
Relative Density.	1.69 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (184.84 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3105 mL	11.5527 mL	23.1054 mL	115.5268 mL
5 mM	0.4621 mL	2.3105 mL	4.6211 mL	23.1054 mL
10 mM	0.2311 mL	1.1553 mL	2.3105 mL	11.5527 mL
20 mM	0.1155 mL	0.5776 mL	1.1553 mL	5.7763 mL
50 mM	0.0462 mL	0.2311 mL	0.4621 mL	2.3105 mL
100 mM	0.0231 mL	0.1155 mL	0.2311 mL	1.1553 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc