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12-PAHSA

Catalog No. T36586 CAS 1997286-65-3

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 12-PAHSA is a FAHFA in which palmitic acid is esterified at the 12th carbon of hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue. 12-PAHSA is present at 2- to 3-fold higher levels in adipose tissue of AG4OX mice compared to wild type mice. Levels of 12-PAHSA are also higher in fasted wild-type mice compared to fed mice and are reduced upon high-fat diet-induced obesity in insulin-resistant mice.

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12-PAHSA, CAS 1997286-65-3

Pack Size	Availability	Price/USD
1 mg	35 days	$ 155.00
5 mg	35 days	$ 675.00
10 mg	35 days	$ 1,190.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	538.898
Formula	C34H66O4
CAS No.	1997286-65-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL

DMSO: 15 mg/mL

DMF: 20 mg/mL

Ethanol: 20 mg/mL

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Keywords

12-PAHSA 1997286-65-3 12PAHSA 12 PAHSA inhibitor inhibit

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