Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 90 nM.SLP9101555 has a high affinity for SphK2, which is 200-fold higher than that of SphK1.SLP9101555 dramatically reduces extracellular S1P sphingosine 1-phosphate (S1P) levels.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 350.00 | |
5 mg | In stock | $ 828.00 | |
10 mg | In stock | $ 1,130.00 | |
25 mg | In stock | $ 1,590.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 | |
500 mg | In stock | $ 4,900.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 698.00 |
Description | SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 90 nM.SLP9101555 has a high affinity for SphK2, which is 200-fold higher than that of SphK1.SLP9101555 dramatically reduces extracellular S1P sphingosine 1-phosphate (S1P) levels. |
Targets&IC50 | SPHK1:18000 ± 220 nM(Ki), SPHK2:90 ± 11 nM(Ki) |
In vivo | SLP9101555 (compound 14c) (5 mg/kg; I.P.; single) leads to a remarkable elevation of blood S1P levels.[1] |
Molecular Weight | 357.72 |
Formula | C16H22BrClN2 |
CAS No. | T63047 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.72 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SLP9101555 T63047 GPCR/G Protein LPL Receptor S1P Receptor inhibitor inhibit