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Anti-Renin Antibody (1Q991)

😃Good
Catalog No. TMAY-03207
Alias renin, REN, HNFJ2, FLJ10761

Anti-Renin Antibody (1Q991) is a Rabbit antibody targeting Renin. Anti-Renin Antibody (1Q991) can be used in ELISA,IHC-P.

Anti-Renin Antibody (1Q991)

Anti-Renin Antibody (1Q991)

😃Good
Catalog No. TMAY-03207Alias renin, REN, HNFJ2, FLJ10761
Anti-Renin Antibody (1Q991) is a Rabbit antibody targeting Renin. Anti-Renin Antibody (1Q991) can be used in ELISA,IHC-P.
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100 μL254 € 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Renin Antibody (1Q991) is a Rabbit antibody targeting Renin. Anti-Renin Antibody (1Q991) can be used in ELISA,IHC-P.
Aliasrenin, REN, HNFJ2, FLJ10761
Ig Type
Monoclonal Rabbit IgG
Clone
1Q991
Reactivity
Mouse
Verified Activity
Immunochemical staining of mouse REN1 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to juxtaglomerular cell. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
Application
ELISA,IHC-P
Recommended Dose
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse REN1 (rM REN1; TMPY-01231; NP_112469.1; Met 1-Arg 402).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundRenin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse REN1 protein (TMPY-01231)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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