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Anti-Renin Antibody (1Q991)
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Catalog No. TMAY-03207
Alias renin, REN, HNFJ2, FLJ10761
Anti-Renin Antibody (1Q991) is a Rabbit antibody targeting Renin. Anti-Renin Antibody (1Q991) can be used in ELISA,IHC-P.
Anti-Renin Antibody (1Q991)
Anti-Renin Antibody (1Q991)
😃Good
Catalog No. TMAY-03207Alias renin, REN, HNFJ2, FLJ10761
Anti-Renin Antibody (1Q991) is a Rabbit antibody targeting Renin. Anti-Renin Antibody (1Q991) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA, IHC-P Reactivity: Mouse |
| Alias | renin, REN, HNFJ2, FLJ10761 |
| Ig Type | Rabbit IgG |
| Clone | 1Q991 |
| Reactivity | Mouse |
| Verified Activity | Immunochemical staining of mouse REN1 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to juxtaglomerular cell. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein). |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse REN1 (rM REN1; TMPY-01231; NP_112469.1; Met 1-Arg 402). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse REN1 protein (TMPY-01231) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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