Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Boc-NHCH2CH2-PEG1-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | Boc-NHCH2CH2-PEG1-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Boc-NHCH2CH2-PEG1-azide |
Molecular Weight | 230.2642 |
Formula | C9H18N4O3 |
CAS No. | 176220-30-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Boc-NHCH2CH2-PEG1-azide 176220-30-7 BocNHCH2CH2PEG1azide Boc-NHCH-2CH2-PEG1-azide Boc NHCH2CH2 PEG1 azide inhibitor inhibit