Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Tributyl phosphate

🥰Excellent
Catalog No. T20271Cas No. 126-73-8
Alias NSC-8484, NSC8484, NSC 8484

Tributyl phosphate (NSC 8484, Tributyl phosphate) is a trialkyl phosphate that is often used as a solvent, plasticizer, and extractant, including in extraction processes involving transuranic elements and rare earth metals.

Tributyl phosphate

Tributyl phosphate

🥰Excellent
Catalog No. T20271Alias NSC-8484, NSC8484, NSC 8484Cas No. 126-73-8
Tributyl phosphate (NSC 8484, Tributyl phosphate) is a trialkyl phosphate that is often used as a solvent, plasticizer, and extractant, including in extraction processes involving transuranic elements and rare earth metals.
Pack SizePriceAvailabilityQuantity
1 g$30In Stock
10 g$45In Stock
Add to Cart
Add to Quotation
Bulk & Custom
Questions
View More
Select Batch
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Tributyl phosphate (NSC 8484, Tributyl phosphate) is a trialkyl phosphate that is often used as a solvent, plasticizer, and extractant, including in extraction processes involving transuranic elements and rare earth metals.
In vitro
In GC-2 mouse spermatocyte cells, Tributyl phosphate exposure (10, 50, 200 μM for 24 h) reduced cell viability, induced apoptosis, and decreased the BCL2/BAX ratio. At 50 and 200 μM, Tributyl phosphate also triggered reactive oxygen species (ROS) accumulation and a loss of mitochondrial membrane potential, indicating oxidative stress-mediated cytotoxicity[1].
In vivo
Male ICR mice orally administered TBP (50 and 100 mg/kg/day for 35 days) showed reduced sperm count and motility, testicular structural damage, and increased testicular cell apoptosis. Tributyl phosphate also caused gut microbiota dysbiosis, increased the abundance of Prevotellaceae (negatively correlated with sperm motility), and promoted Th17 cell infiltration in the small intestine along with IL-17A signaling activation in the testes, suggesting that Tributyl phosphate induces male reproductive toxicity via the gut–testis axis, oxidative stress, and inflammation[1].
AliasNSC-8484, NSC8484, NSC 8484
Chemical Properties
Molecular Weight266.31
FormulaC12H27O4P
Cas No.126-73-8
SmilesO=P(OCCCC)(OCCCC)OCCCC
Relative Density.0.979
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5 mg/mL (18.78 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7550 mL18.7751 mL37.5502 mL187.7511 mL
5 mM0.7510 mL3.7550 mL7.5100 mL37.5502 mL
10 mM0.3755 mL1.8775 mL3.7550 mL18.7751 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Tributyl phosphate | purchase Tributyl phosphate | Tributyl phosphate cost | order Tributyl phosphate | Tributyl phosphate chemical structure | Tributyl phosphate in vivo | Tributyl phosphate in vitro | Tributyl phosphate formula | Tributyl phosphate molecular weight