Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PARP-2-IN-3 is used as a potent PARP-2 inhibitor (IC50=0.07 μM) with anti-tumor activity that induces apoptosis and necrosis in cancer cells, and can be used for the study of breast cancer.CAS 번호128-52-56-8
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 350.00 | |
5 mg | In stock | $ 970.00 | |
25 mg | In stock | $ 1,590.00 | |
50 mg | In stock | $ 1,980.00 |
Description | PARP-2-IN-3 is used as a potent PARP-2 inhibitor (IC50=0.07 μM) with anti-tumor activity that induces apoptosis and necrosis in cancer cells, and can be used for the study of breast cancer.CAS 번호128-52-56-8 |
Targets&IC50 | PARP2:0.07 μM |
In vitro | PARP-2-IN-3(Compound 12) has been demonstrated as the most potent PARP-2 inhibitor, with IC50 values of 0.07 µM. Compound 12 induces cell cycle arrest at the G2/M and G1/S phases in mutant MCF-7 cell line and exhibits significant apoptosis-inducing activity[1]. |
Molecular Weight | 385.84 |
Formula | C20H20ClN3O3 |
CAS No. | 2915650-86-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PARP-2-IN-3 2915650-86-9 Apoptosis Chromatin/Epigenetic DNA Damage/DNA Repair PARP inhibitor inhibit