keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,4-dinitrophenyl (Dnp) group for quenching, yielding a significant increase in fluorescence when the substrate is cleaved [1].
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Description | Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,4-dinitrophenyl (Dnp) group for quenching, yielding a significant increase in fluorescence when the substrate is cleaved [1]. |
In vitro | Mca-Ala7,Lys(Dnp)9-Bradykinin serves as a substrate for neprilysin; however, it is hydrolyzed by ECE-1 with tenfold greater efficiency, indicating a selectivity for ECE-1 [1]. |
Molecular Weight | 1388.44 |
Formula | C66H81N15O19 |
CAS No. | 323577-36-2 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Mca-(ala7,lys(dnp)9)-bradykinin 323577-36-2 inhibitor inhibit