B7-H3 Protein, Cynomolgus, Recombinant (His)

Name: B7-H3 Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPY-04585
Rating: 4.5 (1 reviews)

(Synonyms: CD276 molecule) Copy Product Info

Synonyms: CD276 molecule

Catalog No. TMPY-04585 Copy Product Info

B7-H3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.2 kDa and the accession number is XP_015308534.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$48	7-10 days	7-10 days
10 µg	$79	7-10 days	7-10 days
20 µg	$129	7-10 days	7-10 days
50 µg	$250	7-10 days	7-10 days
100 µg	$483	7-10 days	7-10 days
200 µg	$736	7-10 days	7-10 days
500 µg	$1,530	7-10 days	7-10 days
1 mg	$3,150	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Immobilized Cynomolgus B7-H3 (4Ig), His Tag at 1 μg/ml (100 μl/Well) on the plate. Dose response curve for Anti-B7-H3 Antibody, hFc Tag with the EC50 of 5.5 ng/ml determined by ELISA.
Description	B7-H3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.2 kDa and the accession number is XP_015308534.1.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	XP_015308534.1
Construction	Leu29-Glu465
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	CD276 molecule
Research Background	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Chemical Properties

Molecular Weight

48.2 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.