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Anti-MCP-3/CCL7 Antibody-PE (4B549)
🥰Excellent
Catalog No. TMAY-02144P
Anti-MCP-3/CCL7 Antibody-PE (4B549) is a PE-conjugated Mouse antibody targeting MCP-3/CCL7. Anti-MCP-3/CCL7 Antibody-PE (4B549) can be used in FCM.
Anti-MCP-3/CCL7 Antibody-PE (4B549)
Anti-MCP-3/CCL7 Antibody-PE (4B549)
🥰Excellent
Catalog No. TMAY-02144P
Anti-MCP-3/CCL7 Antibody-PE (4B549) is a PE-conjugated Mouse antibody targeting MCP-3/CCL7. Anti-MCP-3/CCL7 Antibody-PE (4B549) can be used in FCM.
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Chemical Properties
| Description | Anti-MCP-3/CCL7 Antibody-PE (4B549) is a PE-conjugated Mouse antibody targeting MCP-3/CCL7. Anti-MCP-3/CCL7 Antibody-PE (4B549) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4B549 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CCL7 expression on THP1 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE-conjugated anti-Human CCL7. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MCP-3 / CCL7 (rh MCP-3 / CCL7; NP_006264.2Gln24-Leu99) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 7(CCL7), also known as MCP-3, is a isform of the C-C chemokine subfamily of the chemokine family which is produced by certain tumor cells and by macrophages. It also own two adjacent N-terminal cysteine residues. Chemokine ligand 7(CCL7) spacifically attracts monocytes, and regulates macrophage function. |
| Conjucates | PE |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human MCP-3 / CCL7 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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