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p-Hydroxyphenethyl anisate

Name: p-Hydroxyphenethyl anisate
Brand: TargetMol
SKU: TN1275
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1275Cas No. 87932-34-1

Alias 4-Hydroxyphenethylanisate

p-Hydroxyphenethyl anisate (4-Hydroxyphenethylanisate), a natural product from Notopterygium forbe-siiBoiss, is a novel polymeric sustained-release material that, after block copolymerization with AAPBA, produces nanoparticles with good pH sensitivity, glucose sensitivity, insulin loading rate, and stability.

p-Hydroxyphenethyl anisate

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Purity: 99.95%

Catalog No. TN1275Alias 4-HydroxyphenethylanisateCas No. 87932-34-1

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	-	In Stock
5 mg	$51	-	In Stock
10 mg	$83	-	In Stock
25 mg	$140	-	In Stock
50 mg	$209	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.95%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

p-Hydroxyphenethyl anisate AI Summary

p-Hydroxyphenethyl anisate exhibits a wide range of bioactivities based on various assays. It modulates miRNAs and activates miR-21, alongside inhibiting miR-21. Additionally, it activates Rab9 and NPC1 promoters, enhances SMN2 splice variant expression, and acts as an inhibitor of Tau fibril formation, ROR gamma transcriptional activity, and Influenza NS1 protein function. Moreover, it inhibits AmpC Beta-Lactamase, ELG1-dependent DNA repair, TDP-43, and cell surface uPA generation. The compound displays inhibitory effects on the binding or entry of Lassa Virus and Marburg Virus into cells and acts as a reverse agonist of the GLP-1 Receptor. It has antiviral properties against the Foot and Mouth Disease Virus, induces genotoxicity in HEK293T cells, and shows delayed death inhibition of the malarial parasite plastid. Furthermore, p-Hydroxyphenethyl anisate is involved in modulating firefly luciferase activity and activates BRCA1 expression..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	p-Hydroxyphenethyl anisate (4-Hydroxyphenethylanisate), a natural product from Notopterygium forbe-siiBoiss, is a novel polymeric sustained-release material that, after block copolymerization with AAPBA, produces nanoparticles with good pH sensitivity, glucose sensitivity, insulin loading rate, and stability.
Synonyms	4-Hydroxyphenethylanisate

Chemical Properties

Molecular Weight	272.3
Formula	C₁₆H₁₆O₄
Cas No.	87932-34-1
Smiles	C(OCCC1=CC=C(O)C=C1)(=O)C2=CC=C(OC)C=C2
Relative Density.	1.199 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (201.98 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6724 mL	18.3621 mL	36.7242 mL	183.6210 mL
5 mM	0.7345 mL	3.6724 mL	7.3448 mL	36.7242 mL
10 mM	0.3672 mL	1.8362 mL	3.6724 mL	18.3621 mL
20 mM	0.1836 mL	0.9181 mL	1.8362 mL	9.1811 mL
50 mM	0.0734 mL	0.3672 mL	0.7345 mL	3.6724 mL
100 mM	0.0367 mL	0.1836 mL	0.3672 mL	1.8362 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc