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PAP Protein, Human, Recombinant (His)

(Synonyms: PDGF-Associated Protein, PDGFA-Associated Protein 1, PDAP1, PAP1, PAP, HASPP28, 28 kDa Heat- and Acid-Stable Phosphoprotein) Copy Product Info

Synonyms: PDGF-Associated Protein, PDGFA-Associated Protein 1, PDAP1, PAP1, PAP, HASPP28, 28 kDa Heat- and Acid-Stable Phosphoprotein

Catalog No. TMPJ-01107 Copy Product Info
Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$11235 days35 days
10 μg$18335 days35 days
20 μg$29235 days35 days
50 μg$54535 days35 days
100 μg$79235 days35 days
200 μg$1,15035 days35 days
500 μg$1,90035 days35 days
1 mg$2,73035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.
Species
Human
Expression System
E. coli
TagN-6xHis
Accession NumberQ13442
Amino AcidMet1-Lys181
ConstructionMet1-Lys181
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 0.1 mM PMSF, 2 mM DTT, pH 8.0.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsPDGF-Associated Protein, PDGFA-Associated Protein 1, PDAP1, PAP1, PAP, HASPP28, 28 kDa Heat- and Acid-Stable Phosphoprotein
Research Background
Chemical Properties
Molecular Weight30 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: PAP Protein, Human, Recombinant (His) chemical structure | PAP Protein, Human, Recombinant (His) molecular weight