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Cariporide

Name: Cariporide
Brand: TargetMol
SKU: T2238
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2238Cas No. 159138-80-4

Alias HOE-642

Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1).

Cariporide

🥰Excellent

Purity: 99.88%

Catalog No. T2238Alias HOE-642Cas No. 159138-80-4

Pack Size	Price	Availability
5 mg	$39	In Stock
10 mg	$55	In Stock
25 mg	$113	In Stock
50 mg	$222	In Stock
100 mg	$346	In Stock
500 mg	$819	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Batch Information

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Purity:99.88%

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COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1).
Targets&IC50	NHE1:30 nM
Synonyms	HOE-642

Chemical Properties

Molecular Weight	283.35
Formula	C₁₂H₁₇N₃O₃S
Cas No.	159138-80-4
Smiles	CC(C)c1ccc(cc1S(C)(=O)=O)C(=O)N=C(N)N
Relative Density.	1.34g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (70.58 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5292 mL	17.6460 mL	35.2920 mL	176.4602 mL
5 mM	0.7058 mL	3.5292 mL	7.0584 mL	35.2920 mL
10 mM	0.3529 mL	1.7646 mL	3.5292 mL	17.6460 mL
20 mM	0.1765 mL	0.8823 mL	1.7646 mL	8.8230 mL
50 mM	0.0706 mL	0.3529 mL	0.7058 mL	3.5292 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc