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Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody
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Catalog No. TMAC-00636
Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cbl-c (Tyr731). Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody can be used in WB.
Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody
Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody
😃Good
Catalog No. TMAC-00636
Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cbl-c (Tyr731). Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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| Description | Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cbl-c (Tyr731). Anti-Phospho-Cbl-c (Tyr731) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | Cbl proto-oncogene(CBL) Homo sapiens This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016], |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human c-Cbl around the phosphorylation site of Tyr731 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 100 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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