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Anti-ITGB1 Antibody-PE (2Z549) is a PE-conjugated Mouse antibody targeting ITGB1. Anti-ITGB1 Antibody-PE (2Z549) can be used in FCM.
Description | Anti-ITGB1 Antibody-PE (2Z549) is a PE-conjugated Mouse antibody targeting ITGB1. Anti-ITGB1 Antibody-PE (2Z549) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 2Z549 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human ITGB1(CD29) expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human ITGB1(CD29). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ITGB1 / Integrin beta-1 / CD29 (rh ITGB1 / Integrin beta-1 / CD29; TMPY-00476; CAA30790.1; Met1-Asp728) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer. |
Conjucates | PE |
Others Formats | Unconjugated/APC/FITC |
Antibody Types Available | 4 |
Immunogen | Recombinant Human ITGB1 / Integrin beta-1 / CD29 Protein (TMPY-00476) |
Antigen Species | Human |
Biology Area | Cardiac Stem Cell Markers |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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