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LP-471756

Name: LP-471756
Brand: TargetMol
SKU: T27850
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T27850Cas No. 413605-11-5

Alias LP471756

LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 nM).

LP-471756

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Purity: 99.76%

Catalog No. T27850Alias LP471756Cas No. 413605-11-5

LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 nM).

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$46	In Stock
25 mg	$96	In Stock
50 mg	$156	In Stock
100 mg	$251	In Stock
200 mg	$353	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock

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Purity:99.76%

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COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 nM).
Targets&IC50	GPR139:640 nM
Synonyms	LP471756

Chemical Properties

Molecular Weight	329.46
Formula	C₁₉H₂₃NO₂S
Cas No.	413605-11-5
Smiles	Cc1ccccc1NS(=O)(=O)c1ccc(cc1)C1CCCCC1
Relative Density.	1.193 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225.0 mg/mL (682.9 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0353 mL	15.1763 mL	30.3527 mL	151.7635 mL
5 mM	0.6071 mL	3.0353 mL	6.0705 mL	30.3527 mL
10 mM	0.3035 mL	1.5176 mL	3.0353 mL	15.1763 mL
20 mM	0.1518 mL	0.7588 mL	1.5176 mL	7.5882 mL
50 mM	0.0607 mL	0.3035 mL	0.6071 mL	3.0353 mL
100 mM	0.0304 mL	0.1518 mL	0.3035 mL	1.5176 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc