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Anti-PRTFDC1 Antibody (6G114)
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Catalog No. TMAY-02682
Alias PRTFDC1, phosphoribosyl transferase domain containing 1, HHGP
Anti-PRTFDC1 Antibody (6G114) is a Mouse antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (6G114) can be used in WB,ELISA.
Anti-PRTFDC1 Antibody (6G114)
Anti-PRTFDC1 Antibody (6G114)
😃Good
Catalog No. TMAY-02682Alias PRTFDC1, phosphoribosyl transferase domain containing 1, HHGP
Anti-PRTFDC1 Antibody (6G114) is a Mouse antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (6G114) can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: WB, ELISA Reactivity: Human |
| Alias | PRTFDC1, phosphoribosyl transferase domain containing 1, HHGP |
| Ig Type | Mouse IgG1 |
| Clone | 6G114 |
| Reactivity | Human |
| Verified Activity | Anti-PRTFDC1 mouse monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:28 kDa. -Observed band size:28 kDa |
| Application | WB,ELISA |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PRTFDC1 (rh PRTFDC1; TMPY-03332; Q9NRG1-1; Met1-Val225). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a severe X-linked neurological disorder caused by a deficiency of hypoxanthine phosphoribosyltransferase. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PRTFDC1 protein (TMPY-03332) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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