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Anti-PRTFDC1 Antibody (6G114)

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Catalog No. TMAY-02682
Alias PRTFDC1, phosphoribosyl transferase domain containing 1, HHGP

Anti-PRTFDC1 Antibody (6G114) is a Mouse antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (6G114) can be used in WB,ELISA.

Anti-PRTFDC1 Antibody (6G114)

Anti-PRTFDC1 Antibody (6G114)

😃Good
Catalog No. TMAY-02682Alias PRTFDC1, phosphoribosyl transferase domain containing 1, HHGP
Anti-PRTFDC1 Antibody (6G114) is a Mouse antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (6G114) can be used in WB,ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PRTFDC1 Antibody (6G114) is a Mouse antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (6G114) can be used in WB,ELISA.
AliasPRTFDC1, phosphoribosyl transferase domain containing 1, HHGP
Ig Type
Monoclonal Mouse IgG1
Clone
6G114
Reactivity
Human
Verified Activity
Anti-PRTFDC1 mouse monoclonal antibody at 1:500 dilution.

-Lane A: 293T Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.

-Developed using the Odyssey technique.

-Performed under reducing conditions.

-Predicted band size:28 kDa.

-Observed band size:28 kDa
Application
WB,ELISA
Recommended Dose
WB: 1:500-1:1000; ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PRTFDC1 (rh PRTFDC1; TMPY-03332; Q9NRG1-1; Met1-Val225). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundPRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a severe X-linked neurological disorder caused by a deficiency of hypoxanthine phosphoribosyltransferase. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human PRTFDC1 protein (TMPY-03332)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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