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Pisiferic acid

Name: Pisiferic acid
Brand: TargetMol
SKU: T71778
Rating: 4.5 (1 reviews)

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Catalog No. T71778Cas No. 67494-15-9

Pisiferic acid is a diterpene antibacterial agent isolated from Chamaecyparis pisifera. This product exhibits potent inhibitory activity against various Gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, with MIC values typically ranging from 1.56 to 12.5 µg/mL. Additionally, it shows moderate inhibitory effects against certain Gram-negative bacteria, such as Proteus vulgaris. It serves as a pharmacological tool for researching natural antibiotics and their structure-activity relationships.

Pisiferic acid

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Catalog No. T71778Cas No. 67494-15-9

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	Inquiry	10-14 weeks	10-14 weeks
50 mg	Inquiry	10-14 weeks	10-14 weeks
100 mg	Inquiry	10-14 weeks	10-14 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Appearance:Solid

Color:White

Resource Download

COA

Product Introduction

Bioactivity

Description

In vitro

Pisiferic acid exhibits potent selective antibacterial activity against Gram-positive strains (S. aureus 209P and B. subtilis PCI 219, MIC=1.56 µg/mL), while showing significantly lower efficacy against Gram-negative P. vulgaris OX 19 (MIC=100 µg/mL) [1].

Chemical Properties

Molecular Weight	316.43
Formula	C₂₀H₂₈O₃
Cas No.	67494-15-9
Smiles	C(O)(=O)[C@@]12C=3C(CC[C@]1(C(C)(C)CCC2)[H])=CC(C(C)C)=C(O)C3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year

Solubility Information

DMSO: 80 mg/mL (252.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1603 mL	15.8013 mL	31.6026 mL	158.0128 mL
5 mM	0.6321 mL	3.1603 mL	6.3205 mL	31.6026 mL
10 mM	0.3160 mL	1.5801 mL	3.1603 mL	15.8013 mL
20 mM	0.1580 mL	0.7901 mL	1.5801 mL	7.9006 mL
50 mM	0.0632 mL	0.3160 mL	0.6321 mL	3.1603 mL
100 mM	0.0316 mL	0.1580 mL	0.3160 mL	1.5801 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc